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Home > Respiratory Function Amongst Asymptomatic Hiv Positive and Hiv Negative Clients at Aga Khan University Hospital, Nairobi

Respiratory Function Amongst Asymptomatic Hiv Positive and Hiv Negative Clients at Aga Khan University Hospital, Nairobi

Thesis Info

Author

Murbiy, Noah Kipkemei

Department

Internal Medicine (East Africa)

Program

MMed

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Subject

Medicine

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676728066506

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Background: Spirometry is used to asses respiratory function abnormalities. This is usually in reference to a validated normal range unique to a particular gender, race, age, weight and height. Majority of persons are usually asymptomatic until the expected FEV1 has decreased by 50%. Early intervention on the abnormalities even in this asymptomatic group has been shown to retard the rate of pulmonary deterioration. An unpublished audit at the Aga Khan University Hospital, Nairobi, revealed that majority of newly diagnosed HIV positive persons were admitted at the Critical Care Units with a pulmonary cause which later resulted in poor outcomes. This study explored possible existence of abnormal baseline respiratory function in HIV patients. Objectives: The primary objective was to determine the association between abnormal spirometry and HIV status amongst clients at the Aga Khan University Hospital, Nairobi. Methods: This was a cross-sectional analytical survey comparing prevalence of abnormal spirometry findings across two populations; asymptomatic HIV positive patients and HIV negative subjects. Results: 57%of the HIV positive subjects had abnormal spirometry findings as opposed to 18% of the HIV negative population. 3% of the abnormal spirometry in the HIV population was obstructive airway disease with restrictive and combined constituting 12% and 85% respectively. 64%of subjects with CD4 counts below 200 had abnormal spirometry results. Conclusion: The prevalence of abnormal spirometry findings was higher in the asymptomatic HIV population with worse function for those with CD4 below 200.
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تری نظر میں رہوں، باوقار ہو جائوں

تری نظر میں رہوں، با وقار ہو جائوں
قسم خدا کی میں رشک بہار ہو جائوں

فدا میں جان کروں تیرے ہر اشارے پر
تری رضا پہ میں ایسے نثار ہو جائوں

فنا مَیں ہو کے تری ذات میں، اے جانِ جاں!
میں کیوں نہ باقی رہوں پائیدار ہو جائوں

ہے میرے پاس یہ نسخہ قرارِ دل کے لیے
کسی کو یاد کروں بے قرار ہو جائوں

مجھے یہ خوف ہے تائبؔ کہ درد ہے جتنا
چھلک پڑوں نہ کہیں زار زار ہو جائوں

افتاء كے فضائل قرآن و حدیث كی روشنی میں

To derive and discover the hidden solution to problems regarding every walk of life, according to the teachings of Islam is called Ijtihad and to convey this solution (answer) to the people concerned is called Ifta. Answers to some queries have been directly given by ALLAH ALMIGHTY Himself Then Allah gave the responsibility to his beloved Prophet Muhammad (SA W) to explain & enlighten the people according to the will of ALMIGHTY ALLAH as Quran And then the same responsibility transfers to the eminent religious scholars (Muftis) who are the true inheritors of the Holy Prophet (SAW) Mufti acts as the deputy of the Holy Prophet (SA W) and holds a very high, important & sensitive position of guiding the people towards Islamic teachings. That is why it needs high care, piety & skill. In the given article the reality, importance and virtues of this highly important position have been enlightened

Constitutionalism and the Dilemma of Judicial Autonomy in Pakistan: A Critical Analysis

This work provides a twofold nature in relation to the law of Pakistan: firstly, constitutionalism being a broad public law concept applies to an analysis of the ongoing development and gradual maturing of this phenomenon in Pakistan. This endeavor helps place the thesis into a rich field of legal and law related literature that examines the trajectories of post-colonial countries in terms of their constitutional struggle and related developments. It provides a more descriptive framework that is useful in its own right as an orderly exposition of largely existing knowledge, ideally with updates on recent significant developments that major scholarly contributions from the earlier times did not yet included. Secondly, this thesis examines the dilemma of judicial activism, which is also referred to as public interest litigation. It endeavors to assess the extent to which judiciary of Pakistan may act as an autonomous entity that can rightfully set itself up as being somehow superior to the other constitutional entities, namely the legislature and the executive. However, the constitutional history of Pakistan elucidates that the role of military is an unavoidable additional stakeholder that impacts the judicial functioning in Pakistan. Constitutionalism not only outlines the sources from where the government derives its authority but also highlights the parameters for the exercise of that power. Montesquieu says that every state performs mainly three functions: legislative, executive, and judicial. To avoid undue concentration of powers, these three functions need to be performed by different bodies. In case, where both legislative and executive functions are performed by one person or body, possibility may arise that tyrannical laws may be enacted by the senate or monarch and those laws be imposed x in despotic manner. Similarly, there could be no liberty if judicial authority is not segregated from the legislative authority or the executive authority. In case where judicial and legislative functions are performed by one body, life and liberty of the people would be at risk to arbitrary control because legislature would be the judge. In case where judicial and executive functions are performed by one body, the judge instead of interpretation of laws may behave with violence and oppression. So, when these three main functions: law making, execution, and adjudication are concentrated in one body that would lead to an untoward position. In the constitutional history of Pakistan, the role of army is that of an unavoidable additional stakeholder and thus significantly impacts the position and role of judiciary. Throughout history, Pakistan has kept on shifting between military and fragile civilian rules where judiciary has often been used to legalize extra constitutional steps especially during military regimes. The establishment of a democratic government with its organs having real independence fairly gives an assurance that judicial autonomy would thrive in future. The Superior Judiciary of Pakistan has facilitated the despotic regimes and its associated interests, which created institutional disequilibrium and consequently undermined representative institutions. After its restoration in March 2009, judiciary asserted an unprecedented autonomy not only from the military regime, but also extended the same attitude towards the civilian government and considered itself as a representative of the public will. Judiciary established a self-conception of public legitimacy and accountability. Judiciary widened the scope of suo motu jurisdiction to a great extent and transgressed its powers of judicial review for so many times, which grappled the whole nation, putting them in a state of disbelief of the existence of an elected democracy. Excessive judicial activism and judicial involvement in every matter of xi the executive can damage the very existence of other state organs. In order to keep the democratic transition on a positive track, judiciary should not intervene excessively in the domain of other state organs. In terms of decision-making, state institutions gives an impression that the whole idea of checks and balances has been compromised. This dictatorial dominance and institutional imbalance has never remained completely unchallenged. Pakistan’s experience with judiciary suggests a rational compromise between judicial autonomy and its constraints. Maximum judicial autonomy, without any constraint, would certainly create impediments to the smooth-functioning of representative institutions and may consequently further strengthen the military and its affiliated interests. This current shift of democratic regime inevitably entails institutions with strong governing capacities, in order to rein in the ambitious military and to uphold the spirit of constitutionalism.