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Home > Risk of Contrast Induced Nephropathy in Hiv Patients Receiving Radiographic Contrast at Three Aga Khan Hospitals

Risk of Contrast Induced Nephropathy in Hiv Patients Receiving Radiographic Contrast at Three Aga Khan Hospitals

Thesis Info

Author

Mwanzi, Sitna A.

Department

Internal Medicine (East Africa)

Program

MMed

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2009

Thesis Completion Status

Completed

Subject

Medicine

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676728067332

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Aim: To study the influence of HIV infection on the development of contrast induced nephropathy in patients receiving radio contrast material Design: Prospective cohort study Patients and setting:One hundred and twenty five (125) HIV positive patients and one hundred and fifty five (155) HIV negative patients selected from in and out patient departments of the Aga Khan University Hospital, Nairobi and Aga Khan Hospitals in Mombasa and Kisumu, were evaluated for the study between August 2008 and August 2009. Methodology: Eligible patients undergoing radiological evaluation requiring the use of radio contrast material were consecutively recruited for the study after which their HIV status was determined. A serum creatinine was determined before and 48 hours after administration of radio contrast material. The percentage change between the two values was calculated for each patient. Analysis was then performed to determine the relative risk of development of Contrast Induced Nephropathy for the HIV positive arm in relation to the HIV negative arm Results: The incidence of contrast induced nephropathy was 12% in the HIV positive group and 14.2% in the HIV negative group (p=0.59) resulting in a non significant relative risk of 0.85 (95 % C.I: 0.458, 1.560). Conclusions: Our findings indicate that HIV infection does not significantly influence the development of contrast induced nephropathy.
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پروفیسر سید حسن

پروفیسر سید حسن مرحوم
افسوس کہ ۱۸؍ نومبر ۸۸؁ء کی صبح ۳۰:۸ بجے اردو اور فارسی کے نامور معلم محقق جناب پروفیسر سید حسن کا پٹنہ میڈیکل کالج میں انتقال ہوگیا، اناﷲ وانا الیہ راجعون۔ چند دنوں پہلے ان پر فالج کا حملہ ہوا تھا، انتقال کے وقت ان کی عمر تقریباً ۷۸ برس کی تھی۔
وہ ۱۹۱۱؁ء میں اپنے نانہالی گاؤں شیخ پورہ ضلع مونگیر میں پیدا ہوئے، اسی ضلع کا الہرہ گاؤں ان کا آبائی وطن تھا، یہاں کے سادات کا تعلق حضرت سید احمد جاجنیریؒ سے ہے، پروفیسر سید حسن کا خاندان بھی جاجنیری تھا، والدہ کا سلسلہ نسب حضرت مخدوم شیخ شعیبؒ برادر عم زاد حضرت شیخ شرف الدینؒ احمد یحییٰ منیری سے ملتا ہے، جب وہ ۷؍۸ سال کے تھے تو ان کے والد کا انتقال ہوگیا، لیکن ماں کی شفقت و تربیت نے یتیمی اور محرومی کا احساس نہ ہونے دیا اور نامساعد حالات کے باوجود وہ تعلیمی مراحل طے کرتے رہے اور مڈل، میڑک، انٹر اور پھر گریجویشن کے سارے امتحانات میں اول آئے، ۳۵؁ء میں اردو میں ۳۷؁ء میں فارسی میں ایم اے کیا، ۳۶؁ء میں انھوں نے ایجوکیشن میں ڈپلوما بھی لیا، بعد میں ۱۹۰۶؁ء میں انھوں نے دانش گاہ تہران ایران سے فارسی جدید، زبان پہلوی اور فارسی قدیم میں ڈپلوما حاصل کیا، طہران میں ڈاکٹر نذیر احمد اور پروفیسر سید امیر حسن عابدی وغیرہ بھی ان کے ساتھ تھے۔تعلیم ختم ہونے کے بعد ان کے مشغلہ تدریس کا آغاز ہوا، ۳۷؁ء میں بہار نیشنل کالج میں وہ فارسی اردو کے لکچرر مقرر ہوئے، ۷ سال کے بعد ۴۴؁ء میں پٹنہ کالج میں لکچرر مقرر ہوئے اور اسی کالج میں وہ ۵۰؁ء میں اسسٹنٹ پروفیسر اورچھ سال کے بعد ترقی کرکے ۶۱؁ء تک پروفیسر رہے، اسی عرصہ میں حکومت بہار نے عربی و فارسی میں مطالعہ و...

ایسر التفاسیر اور اضواء البیان فی تفسیر القرآن کا تقابلی مطالعہ

The ancient 5000 BCyears old Indus Valley Civilization, widely recognized as one of the most important early cities of South Asia. It is one of the world’s first cities and contemporaneous with ancient EgyptianCivilizations and Mesopotamian civilizations. Mohenjo-Daro is located west of the Indus Riveraround 28 kilometres (17 miles) from the town of LarkanaDistrict, Sindh, Pakistan. The Indus Valley civilization was entirely unknown until 1921. It was discovered in 1922 by R. D. Banerji, an officer of the Archaeological Survey of India, under the direction of John Marshall, K. N. Mohenjo-Daro does mean 'Mound of the dead'. It is the name given by the locals to the place. The total area of Mohenjo-daro is 620 acres. Numerous objects found in excavation include seated and standing figures, copper and stone tools, carved seals, balance-scales and weights, gold and jasper jewellery, and children's toys. Many important objects from Mohenjo-daro are conserved at the National Museum of India in Delhi and the National Museum of Pakistan in Karachi. In 1939, a representative collection of arteffacts excavated at the site was transferred to the British Museum by the Director-General of the Archaeological Survey of India.

Fabrication and Characterization of Terbium Substituted Ferrites

This dissertation presents the effect of terbium substitution on the structural, magnetic, electrical and dielectric properties of ferrites of nominal compositions Ni1−xTbxFe2O4 and Mg1-xTbxFe2O4 (where x = 0, 0.02, 0.04, 0.06, 0.08, 0.10, 0.12, 0.14, 0.16, 0.18 and 0.20). The samples were initially sintered at 1000 °C and final sintering was performed at 1230 °C in order to prepare homogeneous ferrites. The said ferrites were characterized by X-ray Diffractometry, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy, Energy Dispersive X-ray Spectroscopy, Vibrating Sample Magnetometery and Ferromagnetic Resonance. Phase analysis from XRD patterns reveals that the samples have a cubic spinel structure along with a few traces of second phase recognized as orthorhombic phase (TbFeO3) and this phase becomes more conspicuous as the terbium (Tb) is substituted in Ni1−xTbxFe2O4 and Mg1- xTbxFe2O4 ferrites. The lattice parameter changes non-linearly as a function of Tb content in both series that was attributed to the differences in ionic radii of the cations involved and the solubility limit of terbium ions. A gradual increase in the bulk density was observed with the increase of terbium concentration in both series. FTIR absorption spectra of Ni1−xTbxFe2O4 and Mg1- xTbxFe2O4 ferrites exhibited two main absorption bands in the wave number range 370 cm-1 to 1500 cm-1, thereby confirming the spinel structure. The particle size measured from XRD analysis found to decrease with the increase of Tb substitution. The morphology of the samples indicates that samples are crack free along with a few agglomerates. The inclusion of Tb caused the magnetization index to drop which is due to redistribution of cations on the tetrahedral and octahedral sites. The coercivity is observed to decrease and this trend is deviated at higher concentrations of terbium ions in Ni1−xTbxFe2O4 and Mg1-xTbxFe2O4 ferrites. Ferromagnetic resonance linewidths are ≤ 1000 Oe for most of the samples. The nominal composition Ni.94Tb.06Fe2O4 have minimum linewidth, ΔH = 593 Oe, which is minimum of the reported linewidths for spinel ferrites. Hence these ferrites have potential in high frequency applications. The relative initial permeability generally decreases for all the Tb-substituted samples and these are attributed to the decrease in magnetization. The magnetic loss factor is damped with respect to frequency and has very low values in the high frequency region. The electrical resistivity increases and it is attributed to the hinderence in the hopping mechanism caused by the presence of Tb-ions in these ferrites which enhance hopping length between the cations involved in the conduction mechanism. The study on resistivity as a function of temperature shows that all the samples obey semiconducting behaviour. The drift mobility drops while the activation energy increases in a similar manner as that of resistivity. The samples NiFe2O4 and MgFe2O4 have high dielectric constant as compared to the substituted samples. Hence, introduction of Tb-ions in Ni1−xTbxFe2O4 and Mg1-xTbxFe2O4 decrease the dielectric constant. All the substituted samples indicate small values of dielectric loss. These features make these ferrites suitable for various applications.