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The Prevalence of Malaria and Assessment of the Uptake of Malaria Prevention Measures in Blood Donors in Two Regional Blood Transfusion Centres in Kenya

Thesis Info

Author

Magutu, Valerie

Department

Pathology (East Africa)

Program

MMed

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2014

Thesis Completion Status

Completed

Subject

Medicine

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676728072591

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Transfusion transmitted malaria is one of the most common transfusion transmissible infections and is a threat to blood safety and malaria control in Sub-Saharan African countries where malaria is endemic. The majority of healthy adults living in malaria endemic areas have some degree of immunity to the disease and an asymptomatic low-level parasitaemia is known to exist in a subset of this population. Blood donors recruited from the population are screened using a donor-selection criteria that includes age, weight, self-declared well-being and measurement of vital signs but not history of recent malaria infection or treatment. The Kenya National Blood Transfusion Services does not currently screen donated blood for malaria, opting instead for prophylactic anti-malarial use. This policy is inconsistent with the current WHO guidelines for the prevention of transfusion transmitted malaria, and the national policy guiding malaria treatment which states that antimalarial use is reserved for laboratory confirmed cases. A cross-sectional survey was conducted at two regional blood transfusion centres of differential malarial endemicity to determine the prevalence of malaria in blood donors. Of the 1,100 donors who participated in this study, five donors tested positive for malaria antigen, 3 from the Mombasa RBTC and 2 from the Nairobi RBTC giving an overall prevalence of 0.5% malaria antigen positivity. Only one peripheral blood film examined was positive for malaria yielding a total prevalence of 0.1% slide positivity. The prevalence of malaria in blood donors does not justify the routine use of prophylactic anti-malarias with each transfusion and a blood donor malaria screening algorithm as an alternative to malaria prophylaxis in the prevention of transfusion transmitted malaria should be developed and implemented.
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سدرہ کا مکیں چومے سرکارؐ کے قدموں کو


سدرہ کا مکیں چومے سرکارؐ کے قدموں کو
جبریلِ امیں چومے سرکارؐ کے قدموں کو

سدرہ سے بھی آگے کی رفعت کو چھو آئے
جو خاک نشیں چومے سرکارؐ کے قدموں کو

آفاق بھی کیوں رہتے محروم سعادت سے
جب روئے زمیں چومے سرکارؐ کے قدموں کو

قبلہ کبھی اقصیٰ سے کعبہ نہیں ہو سکتا
جب تک نہ جبیں چومے سرکارؐ کے قدموں کو

سلمانؓ کی قسمت میں برسوں کی مسافت تھی
صدیقؓ وہیں چومے سرکارؐ کے قدموں کو

عرفانؔ کی پلکوں کی حسرت ہی رہی لیکن
طیبہ کی زمیں چومے سرکارؐ کے قدموں کو

Secondary School Teachers Attitude Toward Teaching English as a Second Language: A Comparative Study

The study explores the comparative analysis of secondary school teachers’ attitude toward teaching English as a second language. The major objective of the study was; to find out secondary school teachers’ attitude toward teaching English related to different demographics. The researcher used quantitative research method that was descriptive in nature. The population of the study comprised all the male and female teachers at Secondary level in province of Punjab, Pak istan. The researchers selected the secon dary school teachers in districts: Lahore, Multan, Sialk ot and Vehari as the sample of the study. Questionnaire was used as a research tool for the study. The researchers distributed the questionnaire among the respondents of the study and collected data. For data analysis, researcher used the statistical techniques of mean score, t-test and ANOVA. The findings of the study informed that difference in mean scores of male and female teachers was not significant, t-value = -.075, p=.634>0.05. It was found that there was a significant difference in teachers’ attitude towards teaching English as second language having professional qualification of B.Ed. and M.Ed. at secondary school level, t-value = .521, p=.047<0.05. It was concluded that male and female respondents have almost same type of attitude of teaching English as second language.

A Class of Generalized Estimators of Population Means Using Auxiliary Variables in Single and Two Phase Sampling With Properties of the Estimators

In this study generalized exponential ratio type estimators have been proposed for estimating the finite population mean, using the information from single and two auxiliary variables, under sampling design such as single and two phase sampling. For each proposed estimator bias of order two and mean square error of order one are derived using single and two phase equal probability sampling with single and two auxiliary variables. A class of these estimators have been developed and their bias of order one and mean square errors of order one have been derived. Mathematical comparison has been furnished of the generalized proposed estimators with the existing estimators. Shrinkage estimators of the proposed estimators have been defined along with their mean square errors for single and two phase sampling. To put side by side the proposed estimators with existing estimators, numerical study has been carried out with single and two phase equal probability sampling. It is experiential that the proposed estimators are more efficient than simple random sampling, Ratio, Bhal and Tuteja (1991), Samiuddin and Hanif (2006), Sisodia and Dwivedi (1981), Upadhyaya (1999), Singh and Tailor (2003) and Noor-ul-Amin and Hanif (2012) and others. In case of unequal probability sampling the proposed estimator is also more efficient than the simple random sampling, Ratio, Bhal and Tuteja (1991), Sisodia and Dwivedi (1981) and Singh and Tailor (2003). To study the properties of the estimators, simulation has been carried out and it is evident that the proposed estimators are consistent estimators of population mean. It also shows that normal distribution is the most significant fitted distribution on the proposed estimators.