45. Al-Jathiyah/The Kneeling Down
I/We begin by the Blessed Name of Allah
The Immensely Merciful to all, The Infinitely Compassionate to everyone.
45:01
a. Ha. Mim.
45:02
a. The sending down of this Book - The Divine Qur’an - is from Allah,
b. The Almighty, The All-Wise.
45:03
a. Indeed, there are Wonders of Allah’s Creative Power throughout the celestial realm and the terrestrial world for all who are willing to believe.
45:04
a. And as they exist in your own creation and in the creation of a variety of other living creatures,
b. that HE scatters throughout the terrestrial world are Wonders for a people who are firm in
belief.
45:05
a. And so too in the alternation of the nighttime and the daytime,
b. and in the means of livelihood which Allah sends down from the sky clouds then HE enlivens the land after it had been made lifeless by prolonged exposures to drought,
c. and in the changing of direction, velocity, and temperature of the winds,
d. in all these are Wonders of Allah’s Creative Power for a people who understand.
45:06
a. These are the Messages of Allah,
b. that WE recite/convey to you in all truth.
c. So then in what other kind of a discourse will they ever believe if not in Allah and HIS Messages?
45:07
a. Woe to every impulsive liar and the sinful……
45:08
a. …. who hears Allah’s Messages in The Qur’an being recited to him,
b. and yet he persists in disbelief arrogantly as if he had never heard them.
c. So give him the good...
According to Ibn-e-Taimia and Mujaddad Alf-e-Sani the Samaa’ of Quran is a real beneficial Samaa’ of perfect Muslims, the Samaa’ of poetry comprises of praise of Prophet (SAW), songs of Jihad and Islam are also permissible and admirable in Islam but the Samaa’ of innovators which comprises of opposing Shariah poetry and practicing of music and clapping is totally innovation and sin. It is important to note that unlike Ibn-e-Taimia and Hadrat Mujadad when mark the Samaa’ valid or invalid, by this he means the particular Samaa’ or spiritual songs of Sufis singed and listened with a particular method that melodramatize the people, Ibn-e-Taimia not interested in such type of Samaa’, Hadrat Mujadad also not inclined towards this type of Samaa’ but according to him it is permissible only sometime to remove the spiritual toughness. Both Allama(s) Ibn-e-Taimia and Mujadad Alf-e-Sani believe that during listening Quran or mentioning GOD(ادخ رکز) some intuitive conditions
Various purine derivatives mainly 6 and 8-substituted sulfanylpurines were synthesized and evaluated for their potential antithyroid activity. The basic theme of the research work originated from the idea of combining the two most popular existing antithyroid drugs, namely propylthiouracil (1) and methimazole (2), into a single molecule to get the combined effect of both drugs through a single compound. Interestingly it resulted in 2,8-disulfanyl-1,9-dihydro-6H-purin-6-one (86). The compound was prepared using known method and three major series along with some individual compounds were also synthesized because the structural properties of the purines and their ability to complex with molecular iodine made them potential antithyroid compounds. In this regard, a series of 8-(alkylsulfanyl)-3,9-dihydro-1H- purine-2,6-diones (144-148) was synthesized using 8-sulfanyl-5,9-dihydro-1H-purine- 2,6-dione (84) and respective alkyl halides in aqueous solution; a second series of 6- (Alkylsulfanyl)-9H-purines (149-159) was synthesized using 6-sulfanylpurine monohydrate and respective alkyl halides in aqueous sodium hydroxide solution. Similarly, ethyl (9H-purin-6-ylsulfanyl)acetate (162) was synthesized using 6- sulfanylpurine monohydrate, triethylamine and ethyl chloroacetate in ethanol and 2-(9H- purin-6-sulfanyl)acetohydrazide (163). Ethyl (9H-purin-6-sulfanyl)acetate (162) and hydrazine hydrate were refluxed in ethanol to get the desired product. Both conventional and microwave assisted methods were used. Microwave assisted heating reduced the reaction time and improved the yield. A series of N''-[Substituted phenylmethylidene]-2- (79-purin-6-sulfanyl)acetohydrazides (164-172) was also synthesized by heating 163 and substituted benzaldehydes in ethanol under reflux. The compounds were studied in vitro as well as in vivo for determining their antithyroid effects. Fortunately, most of them showed significant antithyroid activity with a few to be exceptionally good in this respect. The successful exposition of the synthesized compounds endorsed the idea of the research programme. It is certainly not the end but a new start. The 6 and 8 substituted purine derivatives may now be categorized as a new class of antithyroid agents. These compounds can be used as alternate drugs for popular benefit after completing the requisite procedures like evaluation of cytotoxicity, determining metabolic route and clinical trial etc.