مولانا عبدالحئی سہارنپوری
ہندوستان میں عربی علم و ادب و لغت و محاورات کے جو چند مخصوص ماہرین ہیں۔ ان میں ایک مولانا عبدالحئی صاحب سہارنپوری استاد جامعہ عثمانیہ بھی تھے، افسوس کہ انہوں نے ۲۷؍ رمضان ۱۳۴۸ھ کو بمقام حیدرآباد دکن، مرض طاعون میں مبتلا ہوکر وفات پائی، مرحوم کے دادا شیخ الحدیث مولانا احمد علی صاحب سہارنپوری تھے، جو اپنے زمانے میں علم حدیث کے مرجع کل تھے، ان کے صاحبزادہ اور مرحوم مولانا عبدالحئی صاحب کے والد مولانا عبدالرحمان صاحب ادب عربی کے نامور عالم اور عربی کے شاعر تھے، انہوں نے اندلس کی تباہی کے مشہور مرثیہ کی بحروقافیہ میں مولانا حالی مرحوم کے اشارہ سے ہندوستان کی تباہی کا بہت پردرد مرثیہ لکھا تھا، مولانا عبدالحئی مرحوم کی عمر پینتالیس اور پچاس کے درمیان تھی، عربی کے شاعر اور عربی ادب و امثال اور محاورات کے بڑے عالم تھے اور سرکار نظام کی اعانت سے وہ عربی محاورات کا ایک ضخیم لغت فراہم کررہے تھے، افسوس کہ یہ عظیم الشان کارنامہ بھی ان کی موت سے ناتمام رہا۔ اِنَّا لِلّٰہِ وَ اِنَّا اِلَیْہِ رَاجِعُوْنَ۔
میری ان کی ملاقات دارالعلوم ندوہ میں ۱۹۰۶ء میں ہوئی تھی، جہاں آکر وہ بعض فنون کی تکمیل اور جھوائی ٹولہ میں طب کی تعلیم حاصل کرتے تھے۔ یہ دارالعلوم کا عجیب زمانہ تھا، مولانا شبلی مرحوم زندہ تھے، مولانا حمیدالدین صاحب اور مولانا ابوالکلام صاحب کئی کئی مہینے آکر مولانا مرحوم کے پاس رہتے تھے اور ہر وقت علمی چہل پہل اور علم و ادب کی گفتگو رہتی تھی، اس صحبت میں مرحوم بھی شریک رہتے تھے۔
ان کے والد حیدرآباد میں مطب کرتے تھے، اس تعلق سے حیدرآباد جاکر رہے اور جامعہ عثمانیہ میں استاد مقرر ہوئے، ساتھ ہی ولی عہد بہادر نواب معظم جاہ بہادر (ہزبائنس پرنس آف برار) کی استادی و اتالیقی کے منصب پر...
Inter-Faith Harmony and Contemporary Demands: An Analytical Study in the Light of Divine Teachings Abstract Over the course of time and with the rapid increase in human population need for mutual relations become crucial. Resultantly on behalf of this closeness, separation, anti-standpoints and comparisons also emerged. As the time passed by hatred and hypocrisy and other social vices spread on large scale. Thus human society was waiting for such liberator who may lead and work for the betterment of this society. With the dawn of Islamic civilization all such issues were not only resolved but also provided with a model for containing the difference of opinion and multiple traditions under its unique worldview. Islamic History presents itself as a model where the minorities were provided with the opportunities of participating in political, social, educational and collective affairs. Thus in a society where tyranny, injustice, un-forbearance, religious intensity, terrorism and the activities of violating the human rights were very common, were substituted by the Islamic ideal of forbearance. It is argued here that the solution of all these issues was only in religion contrary to what is being claimed about an idea of social harmony where religion is not given its due position. Today it’s our dire need to develop a sense of harmony, modesty, affection and peacefulness among the masses of various religions of Pakistani society. It is further argued that for this very noble cause all the religious scholars and their followers can come forward playing their pertinent role. Keywords: Interfaith harmony, present era, divine books, religious personalities, Peace
Asthma is reversible inflammatory airway disorder in which several cells and cellular elements plays greater role. In Pakistan this disease is very prevalent. No remedy is available for asthma. In allopathic medicines, generally corticosteroids are used to treat asthma. Many herbal remedies are available worldwide which gave very good results but their scientific evaluation and validation in asthma is almost nil. Three herbal plants namely Ephedra, Hedera helix L. and Thymus serpyllum L. are found to be very popular by local people as remedy for asthma in Pakistan. Mostly used as herbal tea and paste for inflammation. In the current research study, these three plants were selected and their extracts were prepared by hydroalcholic and steam distillation process. These extracts were phytochemically screened. The antioxidant activities and IC50 values were measured. The free radical scavenging activity of Ephedra, was 90.08% ± 1.37, Thymus serpyllum L. 80.9% ± 0.5 and Hedera helix L. 78% ± 0.3. Extracts were qualitatively and quantitatively analyzed by TLC, HPLC and UV-spectrometer. The extracts were selected for three topical formulations containing microemulsion, gel and ointment. In-vitro diffusion (flux) was checked by Franz diffusion cells. Effect of dialysis cellulose membrane and natural rabbit skin on the release of medicaments was also analyzed by using Franz cells. The flux, Jss (µg/cm2/h) for microemulsion, gel and ointment of Ephedra on dialysis cellulose membrane and natural rabbit skin were 1.346, 0.79, 0.656 and 0.70, 0.76, 0.641 respectively, For Hedera helix.L. The flux for microemulsion, gel and ointment on dialysis cellulose membrane and natural rabbit skin were 5.10, 4.02, 2.80 and 4.10, 3.10, 1.40 respectively. For Thymus serpyllum L. the flux for microemulsion, gel and ointment on dialysis cellulose membrane and natural rabbit skin were 7.10, 5.02, 3.80 and 6.10, 4.12, 2.40 respectively. The stable formulations were also selected for further characterization including rheological studies, FTIR, XRD, Zeta size and Zeta potential. It was observed that all preparations were significant staistically; with little variation from one another. For in-vivo studies, HPLC analytical methods were developed and validated under ICH guidelines. The in-vivo studies were performed on rabbits. The Pharmacokinetic parameters i.e. Cmax (µg/ml), Tmax (h), AUC (µg/ml) and MRT (h) were analyzed. For topical microemulsion and gel, Cmax were 27.53 µg/ml, 39.12 µg / ml of pseudoephedrine, 70.22 µg /ml, 75.26 µg /ml of hederacoside C and 35.33 µg /ml, 42.13 µg /ml of thymol respectively. For marketed oral syrup, Cmax values were 251.11 µg /ml, of pseudoephedrine 90.11 µg/ ml, of hederacoside C and 95.23 µg/ml of thymol. Maximum plasma concentration for optimized microemulsion and gel was 6 hours for pseudoephedrine 2 hours for hederacoside C and 3 hours for thymol (same values for both formulations). Plasma concentrations of marketed oral syrups were 2 hours, for pseudoephedrine 1 hour for hederacoside C and 2.0 hours for thymol. Area under curves for microemulsion and gel were 418.76 µg/ml/h, 529.81 µg /ml /h, for pseudoephedrine 492.83 µg/ml/h, 613.10 µg /ml /h for hederacoside C and 396.72 µg /ml/h, 498.44 µg /ml /h, for thymol respectively. Areas under curve for oral syrup were 985.35µg/ml/h, 329.58 µg/ ml /h, and 277.96 µg/ml/h for Pseudoephedrine, hederacoside C and thymol. Mean residence time for microemulsion and gel were 14.81 hours, 12.06 hours, 10.03 hours, 12.95 hours and 12.15 hours, 11.36 hours for Pseudoephedrine, hederacoside C.and thymol respectively. Mean residence time for commercially available syrup were 3.85 hours, 4.05 hours and 9.41 hours for Pseudoephedrine, hederacoside C.and thymol Results of all pharmacokinetic parameters were significant (P < 0.05). It is concluded that topical herbal formulations have greater bioavailability as compared to conventional syrups. Thus It has proved that transdermal formulations prepared using these plants had good bioavailability properties in blood plasma. It is further concluded that these traditional herbal formulations were successfully developed, characterized in formulated in to enhanced transdermal drug delivery systems. The sustainability was improved from 6 hours for all formulation to 24 hours.