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Home > Modulation in Antimcrobial Resistance by Using Apple Cider Vinegar and Black Seed Alone and in Combinations in Diabetic Foot Infections

Modulation in Antimcrobial Resistance by Using Apple Cider Vinegar and Black Seed Alone and in Combinations in Diabetic Foot Infections

Thesis Info

Author

Syeda Mahanoor

Supervisor

Muhammad Adil Rasheed

Department

Veterinary

Institute

University of Veterinary and Animal Sciences

Institute Type

Public

Campus Location

Lahore

Affiliation

UVAS

City

Lahore

Province

Punjab

Country

Pakistan

Degree Starting Year

2017

Degree End Year

2019

Viva Year

2019

Thesis Completing Year

2019

Thesis Completion Status

Completed

Page

116

Subject

Pharmacology

Language

English

Other

Year of Viva Voce Exam was heald at UVAS and was Supervised by Muhammad Adil Rasheed in Sept 2019

Added

2021-04-09 16:03:47

Modified

2024-03-24 20:25:49

ARI ID

1676729717574

Similar


The increased emergence of antibiotic resistance is an alarming situation. The present study was designed to check the anti-MRSA and Pseudomonas aeruginosa activity of apple cider vinegar and black seed oil when used alone and in combination with antibiotics ( amoxicillin, imipenem, cefotaxime, and vancomycin) against antibiotic resistant-MRSA and pseudomonas aeruginosa. The samples that were found resistant to each antibiotic were then selected and antibacterial activity of apple cider vinegar and black seed oil alone and in combination with resistant antibiotics were tested, by using well diffusion and broth microdilution method. The MIC of apple cider vinegar found by good diffusion was 2.5% acidity and for black seed, oil MIC was 512ug for pseudomonas aeruginosa and staphylococcus aureus. Broth dilution was performed by checkerboard method and FIC was calculated to check the synergism between test products and antibiotics which results in the reduction MIC of antibiotic making the results positive for our testing products in which all the samples showed partial to complete synergism. For Pseudomonas aeruginosa samples, MIC of cefotaxime, amoxicillin, vancomycin, and imipenem lowered in the ranges of 128ug to 64ug, 512ug to 128ug, 512ug to 128ug, and 128ug to 32ug respectively in combination with apple cider vinegar and with black seed oil 256 to 128ug, 512ug to 128ug, 512ug to 256ug and 128 to 32ug respectively. For Staphylococcus aureus MIC of cefotaxime, amoxicillin, vancomycin, and imipenem lowered in the ranges of 512 to 128ug, 512ug to 64ug, 256ug to 32ug, and 512ug to 128ug respectively in combination with apple cider vinegar and with black seed oil 512 to 128ug, 512ug to 128ug, 256ug to 64ug and 512 to 64ug respectively, hence modulated the bacterial resistance.
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حضرت عبدالمطلب

حضرت عبد المطلب
انکا نام عامر اور لقب شیبہ تھا۔ اپنے والد کے انتقال کے بعد ننھیال کے ہاں مدینہ میں رہے۔ ان کے چچا مطلب انھیں مکہ لائے اور بیٹوں سے بڑھ کر ناز و نعم سے ان کی پرورش کی ۔ اس احسان کے سبب وہ بھی ساری عمر ’’ عبد المطلب‘‘ یعنی مطلب کا غلام کہلاتے رہے۔ یہ وہ عظیم ہستی ہیں جنھوں نے چاہ زمزم کوجسے عمرو بن حرث جرہمی نے بند کر دیا تھا، نکالا۔ وہ شریف النفس اور عبادت گزار تھے ۔ غار حرا میں کھانا پانی ساتھ لے جاتے اور کئی دن تک خدا کی عبادت میں مصروف رہتے تھے۔ رمضان میں اکثر وہاں اعتکاف کیا کرتے تھے۔ مکہ والوں پر جب کبھی کوئی آفت آتی تو اہل مکہ عبد المطلب کو لے کر پہاڑ پر چڑھ جاتے اور اللہ تعالیٰ کے حضور ان کے وسیلہ سے دعا مانگتے جو قبول ہو جاتی تھی ۔
عبد المطلب کی عام نصیحت یہ ہوتی تھی ’’ ظلم و بغاوت نہ کرو اور مکارم ا خلاق حاصل کرو‘‘ لڑکیوں کو زندہ درگور کرنے سے منع کرتے اور چور کا ہاتھ کاٹ ڈالتے تھے ۔ آپ کعبہ کے متولی تھے۔ آپ کے زمانہ میں اصحاب فیل کا واقعہ پیش آیا۔ ۱۲۰ برس کی عمر میں وفات پائی( سیرت المصطفی جان رحمت۔۱۔۳۱)
اصحاب فیل کا قصہ
پیارے رسول ﷺ کی پیدائش سے پچاس رات یا پچپن دن پہلے یمن کا گورنر ابرہہ ہاتھیوں کی فوج لے کر بیت اللہ کو ڈھانے کے لیے حملہ آور ہوا۔اس کی ایک وجہ یہ تھی کہ اس نے یمن کے دارالخلافہ صنعاء میں ایک شاندار گرجا گھر بنایا ۔ اگرچہ گرجا کی عمارت کی تزئین میں اپنی صلاحیتیں وقف کر کے نمونہ روزگار بنا دیا لیکن تمام خوبیوں کے باوجود اس میں دعائے خلیل ’’ رَبَّناَ...

قواعد التفسير نشاتھا وتطورھا

Rules of Tafseer are basically concerned with understanding meaning of the Holy Qur’an and learn how to take advantage of it. This article preliminary defines the importance of Rules of Tafseer of the Qur’an and also elaborates the different terminologies associated with rules of Tafseer and how these rules are made and developed with the passage of time. This paper also provides an insight into the previous and current studies carried out in the field of Rules of Tafseer. In the beginning, the Rules of Tafseer were considered as part of Usool-e-Fiqh, Tafseer and Qur’anic Science. The knowledge and awareness about Rules of Tafseer was actually accumulated from the Holy Qur’an, Hadith, teachings’ of Sahabah (R. A), Usool-e-Fiqh, Arabic grammar, books of Quranic Science and books of Tafseer, while later on new books were introduced in 14th century.

Effects of Energy Flux on the Distribution of Zooplankton in Mangrove Forests Along the Coast of Karachi.

From Northern Arabian Sea bordering Pakistan this is the pioneer study on the diversity, density and effects of mangrove energy flux on zooplankton community structure. The study focusses on three aspects; Mesozooplankton (MZ) abundance, Copepod diversity and effect of mangrove energy flux on MZ. The study was conducted at four stations (OC, HS, SBM and HBM) covering the inshore waters of Manora channel. Annual and seasonal variations in density of 21 zooplankton group was estimated with respect to change in habitat with different environmental influences. Density of these groups were high at 5m depth. The Copepods were the most abundant meso-zooplankton group at all stations except at OC followed by cladoceran, gelatinous zooplankton, nematodes and polychaete larvae respectively. Cladoceran was high in density (127700 Ind-m-3) at OC. Salinity, temperature, dissolved oxygen and Chl a concentration was found to effect the distribution of MZ. 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