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Home > قرآن کریم میں قلب کی مختلف کیفیات اور قلبی امراض کا علاج منتخب تفاسیر کی روشنی: تحقیق مطالعہ برائے ایم فل علوم اسلامیہ

قرآن کریم میں قلب کی مختلف کیفیات اور قلبی امراض کا علاج منتخب تفاسیر کی روشنی: تحقیق مطالعہ برائے ایم فل علوم اسلامیہ

Thesis Info

Author

شبیر احمد

Supervisor

عبد الحمید خان عباسی

Department

Department of Islamic Studies

Program

Mphil

Institute

Allama Iqbal Open University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Page

312ص۔

Subject

Islamic Studies

Language

Urdu

Other

Classification: 297.1227 ش ب ق

Added

2022-07-09 15:11:20

Modified

2023-02-19 12:33:56

ARI ID

1676729843640

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شاہ عزالدین پھلواروی ندوی

شاہ عزالدین پھلواروی ندوی
شاہ عزالدین پھلواروی علمی اور دینی حلقوں کے لئے محتاج تعارف نہیں، اپنے مواعظ اور تصانیف کی وجہ سے خاصے معروف ہیں، ابھی چند ہی مہینہ کی تو بات ہے جب انھیں عربی زبان اور اسلامی علوم میں مہارت کی بناء پر حکومت ہند نے اعزاز عطا کیا تھا، اور معارف نے اس سلسلہ میں انھیں مبارکباد دی تھی، کسے معلوم تھا کہ وہ اتنی جلد اس دنیا سے رخصت ہوجائیں گے۔
ادھر کچھ عرصہ سے ان کی صحت مضمحل رہنے لگی تھی، اس لئے انھوں نے سفر ترک کردیئے تھے، لیکن پورنیہ کے کچھ لوگ ان کے بے حد معتقد تھے، ان کی آرزو تھی کہ وہ اپنی تشریف آوری سے انھیں عزت بخشیں اور انھیں اپنے مواعظ سے مستفید فرمائیں، شاہ صاحب نے ناسازی مزاج کا عذر کیا، مگر جب معتقدین کا اصرار جاری رہا تو آمادہ ہوگئے تاکہ ان کے دلوں کو ٹھیس نہ پہنچے، مومن کے دل کو خوش کرنا بڑے ثواب کا باعث ہے، انھیں اس سلسلہ میں آقائے دو جہاںﷺ کی ہدایات یاد تھیں، اس لئے اپنی تکلیف کو نظرانداز کرکے آمادہ سفر ہوگئے، راستہ بخیر گزرا، پورنیہ پہونچ کر بھی ایک آدھ دن طبیعت ٹھیک رہی لیکن پھر ضعف کے ساتھ درد سینہ کی شکایت محسوس ہوتی، جو برابر بڑھتی رہی، جب مقامی دوا دارو سے طبیعت قابو میں نہ آئی، تو لوگ کسی بڑے ڈاکٹر کو بلانے کے لئے شہر گئے، مگر ساری تگ و دو بے کار ثابت ہوئی اور بالآخر وطن سے دور عزیزوں سے مہجوری کے عالم میں جان جان آفریں کے سپرد کردی، نعش پھلواری لائی گئی اور خاندانی قبرستان میں سپردخاک کئے گئے، وہ مجھ سے عمر میں چند سال بڑے تھے، تعلیم میں بھی دو تین درجے آگے تھے، لیکن طلبائے ندوہ کی انجمن الاصلاح میں میرا ان...

Attitude Towards Science: A Case Study of Higher Secondary Level Students of Sindh Province

This research is conducted, in order to perceive the attitude of higher secondary level students of Sindh towards science. Students (Male = 448, Female = 648) belonging to higher-secondary level (Class-XI & XII) from Hyderabad division were surveyed. Students were divided in Urban (N=455) and Rural (N=641) groups accordingly. “Test of Science Related Attitudes” known as TOSRA, initially developed by (Fraser, 1978) was adapted and translated in Urdu as well, was used as the attitude measurement instrument. Internalk consistancey was checked with Cronbach’s alpha reliability test. After pilot study the test was administrated. Significant difference of the attitude towards science across the students was noticed based on their gender and their locale. The results show that, with small effect size, male students significantly scored higher on almost all of the attitude sub-scales of TOSRA as compared to female students. Interestingly, students belonging to rural areas significantly scored higher with medium effect size on all the attitude sub-scale towards science as compare to students from urban areas.

Brain Enhancers and Their Role in Distinguishing Human Cns from That of Non-Human Primates

BACKROUND: Human sequence acceleration has been reported to have revamped the status of present-day humans over the course of evolution and has immensely contributed to their efficient adaptation to do highly complicated assessments. Human accelerated DNA fragments are those bits of the genome that have experienced frequent sequential changes after the human-chimp split despite being strongly conserved among mammals. Previous studies have indicated that many such accelerated genomic segments happen to harbor cis-regulatory elements, among which enhancers take up the most portion. Enhancers make up the distal category of cis-regulatory elements that could reside many kilobases away from their target genes and contribute in initiation of cell specific gene expression.Recent findings have also brought to our notice that coding region mutations shared with archaic humans were followed by substitutions in regulatory elements that were Homo sapien-unique and hence attributed to anatomically profound modern human traits. Following this deduction, we opted for brain that is the most profoundly adapted organ in the present-day human anatomy, characterizing them as the most cognitively advanced species. We focussed on acceleration of enhancers that express solely in the brain region. With respect to that, craniofacial development due to an increased brain size during the course of primate evolution has also garnered immense attention over the past many years. The relevance of this increase in brain size and its direct impact in formulating the facial mechanics of humans, both archaic and modern, has left many questions unanswered. Climate is one leading factor that imposed evolutionary constraints over the human facial dynamics. While observing such wide variety of facial forms in the present-day human population, it becomes evidently intriguing to probe into genetic factors that might have given in to the forces of natural selection. With the advent of genome wide association studies, we now have a decent collection of single nucleotide polymorphisms that are associated with various facial features. We took nasal morphology as our case study for being nature‟s profound conditioning system in the human body. By keeping out-of-Africa ancient migrations in mind, we observe a drastic climatic shift from an extremely hot-humid environment of Africa to relatively temperate regions of Asia and extremely cold Europe. Following the pattern of nasal variation on these lines, the aim of our study ensures a link between nasal adaptations to climatic change as wide-bulbous noses are significant features of hothumid climate and narrower-taller noses represent a much colder climate. RESULTS: This study relied on empirically confirmed brain exclusive enhancers to avoid any misjudgments about their regulatory status and categorized among them a subset of enhancers with an exceptionally accelerated rate of lineage specific divergence in humans. Among these accelerated enhancers, we found an assorted set of 13 distinct transcription factor binding sites were located that possessed unique existence in humans. 3/13 such sites belonging to transcription factors SOX2, RUNX1/3 and FOS/JUND possessed single nucleotide variants that made them unique to H. sapiensupon comparisons with Neanderthal and Denisovan orthologous sequences. These variants modifying the binding sites in modern human lineage were further substantiated as single nucleotide polymorphisms via exploiting 1000 Genomes Project Phase III data. Long range haplotype (LRH) based tests laid out evidence of positive selection to be governing in African population on two of the modern human motif modifying alleles with strongest results for SOX2 binding site. For nasal phenotype assessment on the basis of genetic variation, we gathered a set of SNPs from six GWAS studies till date, each associated with a particular nasal feature and applied tests so as to determine the pattern of contrasting selection over alleles in regions of climatic opposites. We incorporated 2504 individuals‟ data from 1000 Genomes Project Phase III. We observed 9 such SNPs that made strong cases of positive selection on either of their allelic variants (derived or ancestral). Among them, we also observed SNPs that conspicuously showed varying patterns of selection on either of the alleles in Africa (hot-humid climate) in comparison with four nonAfrican populations (temperate or colder climates), hence, highlighting a climatically driven, contrasting patterns of divergence of alleles that favored a particular nasal phenotype. CONCLUSION: Our study concludes that sequence divergence in the regulatory repertoire of modern humans underlie their vast phenotypic leverage over other species, brain being the crown of all such adaptations. We also concluded that Homo sapien-specific binding site variants in these enhancers are prone to accelerated divergence across the current-day human population and could be involving a functional advantage. We also gauged in this study that nasal type variation in different regions of the world are climatically driven. Our data also highlights the uniqueness of these substitutions, as majority of the human specific substitutions are not shared with Neanderthals and Denisovans. Also, the occurrence of these SNPs in non-coding part of the genome also points towards a new aspect in which cisregulatory evolution could be playing a significant role in devising the nasal morphological mechanics of the present-day human population.