34. Saba/Sheba
I/We begin by the Blessed Name of Allah
The Immensely Merciful to all, The Infinitely Compassionate to everyone.
34:01
a. The Praise and Gratitude is for Allah – the One and Only God of everyone and everything,
b. The One to WHOM belongs whatever is within the celestial realm and whatever is within the terrestrial world, and
c. the Praise be to HIM in the realm of the Hereafter.
d. And HE is All-Wise, All-Aware.
34:02
a. HE Knows whatever goes into the earth and whatever comes out of it, and
b. whatever comes down from the heaven, and whatever goes up into it.
c. HE is The Compassionate, The Forgiving.
34:03
a. And yet those who disbelieve say:
b. ‘The Last Hour will never come upon us.’
c. Say:
d. ‘Yes, indeed, it will!
e. By my Rabb - The Lord - The Knower of all that is beyond the reach of our senses and
perception,
f. it will certainly come upon you.
g. There is nothing even the weight of a speck in the celestial realm and the terrestrial world that escapes HIS Knowledge.
h. As also there is nothing even smaller than that or bigger but it is in a Clear Book.’
34:04
a. Thus HE keeps track of everything so that HE may reward those who believe and practice righteousness.
b. It is they for whom will be forgiveness and a generous provision in the Paradise.
34:05
a. As for those who challenge and strive against OUR Messages in the Qur’an,
b. seeking to undermine them and thwart their purpose,
c. those - for them will be a painful punishment...
Allah Almighty has created everything in pairs. It is a scientific fact that these pairs exist in all things, in vegetable kingdom, even in inorganic matters. There is no doubt that these elements do not exist by themselves. The Holy Quran has mentioned repeatedly this fact in different verses. Marriage in Islam is a divine bond between husband and wife to enjoy the social relationship with each other and is a basic unit of Islamic family system. This article presents the structure of a Muslim Family in the light Islamic teachings.
Genetic polymorphism might be consider as a marker for predisposition of different diseases including leukemia. Glutathione S Transferase has role in metabolism of different types of Xenobiotics to facilitate their excretion from the body. It has also role in the metabolism of the drugs used in chemotherapy for different diseases. There are many genes that exhibit polymorphism but most of them show single nucleotide polymorphism. The deletion of whole gene is rare. GSTM1 and GSTT1 members of glutathione family are polymorphically deleted. Purpose of the study was to investigate deletion of these two isozymes in local Pakistani population and to investigate if any relationship exists in leukemic population. Male and females of healthy and leukemic patient volunteers were selected. Leukemic population was further divided into different groups (ALL, CLL, AML and CML). Biochemical parameters and oxidantion status of all patients and healthy volunteers were measured by kit method and Genetic polymorphism was seen by PCR and gel electrophoresis. Total bilirubin, creatinin, urea and ALT is greater in patients compared to healthy volunteers. Total oxidant status was low while total antioxidant status was high in healthy volunteers compared to patients depending on disease condition. Healthy subjects show 54% deletion of genes (66% and 52% in female and male respectively). Patients show 67% deletion of GSTM1 gene in which ALL 66% (68% and 76%, CLL 70% (80% and 60%), AML 70% (72% and 68%) and CML 62% (60% and 64%) in female and male respectively. GSTT1 deletion found healthy volunteers was 71% and it is 72% and 70% in female and male respectively and was found 70% in leukemic patients. ALL 78% (76% and 80%), CLL 76% (80% and 76%), AML 66% (76% and 76%) and CML 60% (56% and 64%) female and male respectively. All patients and healthy volunteers have more than 50% deletion of GSTM1 and GSTT1 genes. More deletion of GSTM1 was seen in patients than healthy volunteers while local population seems to be more prone to leukemia and may respond less to some chemotherapeutic drugs.