ایلافِ وفا کا تجزیاتی مطالعہ
اخلاق حیدر آبادی
(شعبہ اردو ، رفاہ انٹر نیشنل یونیورسٹی ،فیصل آباد)
شاعری انسانی تخیل کا پُر جمال اور بلیغ اظہار ہے۔ شاعری میں نظم نے انسانی فکر اور ادراک کو مربوط اور پر اعتماد ہو کر آگے بڑھایا ہے۔ آرائش خیال کے لیے کبھی پابند نظم اور کبھی نظم ِ معرا کو خوب پذیرائی حاصل ہوئی۔ پھر آزاد نظم نے نسبتاً انسانی فکری جہتوں کو زیادہ بے باک انداز اور آزادی کے ساتھ پیش کیا ۔اردو شاعری کے منظر نامے میںنظم گو شعرا ابلاغ کی سطح پر پیش رفت کرتے نظر آتے ہیں۔ وقت کے ساتھ نظم کی روایت نے تخلیق کار کو ایک نئے آہنگ سے متعارف کرایا۔
شاعری کی بابت بہت کچھ کہا گیا ہے اور کہا جاسکتا ہے مگر مختصر اور جامع طور پر ہم کولرج اور شیلے کے ہم زبان ہو کر کہہ سکتے ہیں ’’شاعری تخیل کی زبان ہے‘‘ ۔کانٹ نے بہت دل نشین اندازمیں اپنی کتاب ’’انتقادِ محاکمہ(Aesthetic judgment of critique) ‘‘ میں اپنے کلیدی جملہ میں اپنے نظریہ تخیل کا خلاصہ یوں پیش کیا ہے
’’ تخیل اس مواد سے جو فطرت اس کے لیے مہیا کرتی ہے،ایک فطرتِ ثانی تخلیق کرنے والا ایک زبر دست عامل ہے‘‘(۱)
شاعر یا تخلیق کار کے پاس اظہار کے لیے جو چیز اساس بنتی ہے۔ وہ اس کا احساسِ تخیل ہے۔ ابلاغ کے لیے علامت، استعارہ ،مشاہدہ اور تجربہ تو ہوتا ہے۔ بلکہ الفاظ کے انتخاب کا کڑا فیصلہ بھی شاعر کو ہی کرنا پڑتا ہے۔ اسی طرح نظم کا نام بلا شبہ علامت ہے۔ کسی چیز کی ماہیت نہیں ۔ شعریات کو صنف میں علامتی سطح پر وابستہ کیا جا سکتا ہے۔ حالی ؔ کا یہ قول’’ نفسِ شعر وزن کا محتاج نہیں‘‘ اب تک ایک بامعنی اور راہنما ہے۔ عبدالسمیع اپنی کتاب ’’اردو میں...
Islam is a complete code of life. It is a legal system which fulfills the fundamental and natural rights of human beings. One of these rights is that no action will be taken against anybody if there is received any allegation against him until he is heard. The Islamic law provides the respondent a right to be informed through a show cause notice (SCN) for investigation of the situation whether the allegation against him is true or false. The contemporary laws also assert for security of human rights, but day to day happenings often put them to face many hurdles in its implementation in all such situations, which call further legislation and amendments. This article discusses the SCN procedure in Qur᾽anic perspective. The main purpose is to introduce the compliance and universality of the Islamic law and to make reader know that this law belief (in, on) human rights is to be enhanced for peace and prosperity of human society. There are a bundle of examples in Qur᾽an which clarifies the procedure of a SCN. We have taken just four stories amongst these verses. All of these stories have a complete SCN procedure; from beginning to the end. The procedure is dealt in a descriptive method, accompanied with the SCN procedure in contemporary law also. The conclusion is given at the end that the contemporary law in this aspect is according to the Qur᾽anic instructions.
This dissertation reports physicochemical behaviour of some amphiphilic drugs as well as their interaction with anionogenic tensides (ionic surfactants) and Human serum albumin (HSA). A detail study of self aggregation of these drugs i.e. Clindamycine Phosphate (CLN), Quinacrine 2HCl (QUN), Chloroquine diphosphate (CLQ), Dexamethasone Sodium Phosphate (DSP) , Pefloxacin Mesylate (PFL), Citalopram HBr (CIT), Fluphenazine 2HCl (FLP), Trifluperazine 2HCl (TRF) and Certizine 2HCl (CRT) has been worked out. Surface tension and specific conductivity were measured to calculate the critical micelle concentration (CMC) of drugs and in this way their surface and thermodynamic parameters have been estimated. Surface activity was studied by measuring surface parameters i.e. surface pressure, Л, surface excess concentration, Г, area per molecule of ° drug and standard Gibbs free energy of adsorption, DGads . The electrical conductivity was measured as a function of concentration in the temperature range of 293-323K and CMC was determined. Consequently ° thermodynamic parameters like standard free energy of micellization, DGm , standard ° ° enthalpy of micellization, DH m and standard entropy of micellization, DS m were computed using closed association model. Aggregation properties of some structurally related drugs trifluperazine and fluphenazine and Quinacrine and Chloroquine have also been brought under study. For the most of drugs, association was found to be both enthalpy as well as entropy driven. Dexamethasone sodium phosphate, however, undergoes open association rather than micellization. We have also studied interaction of amphiphilic drugs with anionic surfactants sodium dodecyl sulfate (SDS) and cationic surfactant cetyltrimethyl ammonium bromide (CTAB). Aqueous micellar solutions of these surfactants were used for solublization of these drugs. The change of CMC of surfactant due to drug was determined by UV/Visible spectroscopy and conductivity method. UV/Visible spectroscopy was used to check the qualitative and quantitative features of this interaction and to calculate partition coefficient (Kx), free energy of partition and number of drug molecules per micelle while conductivity method is helpful to calculate different thermodynamic parameters. The complexation of amphiphilic drugs with HSA at physiological conditions (pH 3.0 and 7.4) have also been analyzed by using UV/Visible spectroscopy, fluorescence spectroscopy and dynamic laser light scattering. In this way values of drug-protein binding constant, number of binding sites and hydrodynamic radii were calculated and discussed in detail.