ریاضؔ خیرآبادی
ملک میں یہ خبر نہایت افسوس کے ساتھ سنی جائے گی کہ ہماری زبان کے مشہور کہنہ مشق اور استاد شاعر حضرت ریاض خیر آبادی نے نوے برس کی عمر میں ۱۷؍ ربیع الآخر کو وفات پائی، مرحوم اپنے صف سخن میں باکمال و بے مثال شاعرتھے، اﷲ تعالیٰ ان کو اپنی مغفرت کی شراب طہور سے سیراب فرمائے۔ (سید سلیمان ندوی، اگست ۱۹۳۴ء)
In Arabic language the source from which all nouns and verbs are derived is called (المصدر). Verbal noun (Al-Masdar: (المصدر is a very important derivative in Arabic. It is a noun derived from the verb to refer to the action or activity implied in the verb, e. G. ((كتابة “writing” as a process- derived from the verb (كتب) to “write”. A verbal noun represents a change in the form of a verb which allows it to be used as a noun in a sentence. Verbal noun is a type of noun which can bear the article (ال) or tanwin (تنوين ) and can be declined according to the sentence i.e. Nominative, accusative and genitive case. This article deals with the verbal nouns in the Holy Quran that appeared once in the nominative case and in other Qiraat it was read as accusative case. For e.g. (Al-Hamd) is read as nominative and accusative form. الرفع على قراءة حفص: ( الحمدُ لله رب العالمين ) و فى قراءة أخرى : ( الحمدَ لله رب العالمين ) Likewise other examples are: (سورةٌ أنزلناها )- (سورةً أنزلناها) (سلامٌ عليك)- (سلامًا عليك) Similarly : النصب على قراءة حفص: ( و بالوالدين إحسانًا) و فى قراءة أخرى : ( و بالوالدين إحسانٌ) Thus, the article highlights the semantic treasures embedded in the Qiraat of the Holy-Quran.
Current research project was conducted to study the urinary excretion of deferoxamine, ferrioxamine, iron and zinc in β-thalassemia population. Oxidative stress and antioxidant status was also measured in β-thalassemic patients under indigenous conditions. Blood specimens were collected from both healthy and thalassemic subjects of age less than 15 years without drug administration. Hematological (red blood cells, hemoglobin, MCH, MCV, MCHC, plt, hct, RDW, eiosinophils, monocytes, neutrophils, lymphocytes) and biochemical parameters (triglycerides, cholesterol, LDL, ALT, AST, urea, total protein, albumin, globulin and creatinine) were determined in both healthy and thalassemic populations to check the health status. Oxidant and antioxidant status was studied with the help of spectrophotometer and HPLC. Thalassemic patients were observed in state at higher level of oxidative stress because free iron in body acts as free radical to enhance the oxidative stress. Antioxidants are (either enzymatic or non enzymatic) substances in body which reacts with these free radicals to stop chain reaction. So, the levels of antioxidant vitamins (E, C and β-carotene) were significantly decreased in β- thalassemic patients. Urine samples were collected at 0, 6, 8, 12, 24 h from β-thalassemic patient after 500 mg subcutaneous infusion of deferoxamine. Concentration of deferoxamine and ferrioxamine was determined with the help of HPLC highest concentration of DFO and FO was recorded in urine samples collectes at 6 th hour. % dose of DFO and FO excreted (3 and 2.97 percent) in β-thalassemic patients within twenty four hours. While the concentration of iron and zinc was determined with the help of AAS and cumulative amount excreted of zinc and iron after 24 hours were 1.57 ± 0.06 mg and 30.47 ± 1.47 respectively in thalassemic patients indicating enhanced excretion of zinc. This study would help in clinical investigations and to design better therapeutic protocols under indigenous conditions.