قافلہ کا آخری مُسافر
نواب وقارالملک مرحوم
علم والے علم کا دریا بہا کر چل دیئے
واعظانِ قوم سوتوں کو جگا کر چل دیئے
کچھ سخنور تھے کہ سحر اپنا دکھا کر چل دیئے
کچھ مسیحا تھے کہ مردوں کو جلا کر چل دیئے
. نواب محسن الملک کی وفات پر ہم نے تدبر و سیاست کا ماتم کیا، مولانا نذیر احمد کے مرنے پر سحر نگاری اور بزم آرائی کا مرثیہ پڑھا، مولانا شبلی کی موت پر ہم نے علم کے فقدان پر نوحہ کیا، لیکن نواب وقارالملک کی رحلت پر ہم قوم کا ماتم کرتے ہیں اور الوالعزمانہ اخلاق کی گم شدگی پر فریاد۔
یہ ہستی گراں مایہ جس نے ہماری دنیا کو ۲۷، جنوری ۱۹۱۷ء میں الوداع کہا، ہمارے کارفرما قافلہ کا آخری مسافر تھا، اس کے بعد وہ دور جو انقلاب ہند کے بعد شروع ہوا تھا ختم ہوگیا، وہ دور جو انگریزی کالجوں کی کائنات نہیں، بلکہ بوریا نشین مدارس کا نتیجہ تھی، گزرگیا، وہ دور جو قدیم تعلیم اور قدیم اخلاق کے دنوں کو پیش کرتا تھا، منقطع ہوگیا، یعنی آئندہ ہماری قسمت کے مالک عربی مدارس کے شملے نہ ہونگے، بلکہ انگریزی درسگاہوں کے ہیٹ ہونگے، اب مشرق، مشرق کی قومیت پر حکومت نہیں کرے گا، بلکہ مغرب، اب لیڈری اور رہبریٔ جمہور کے لئے جوش دل اور اخلاص عمل ضروری نہ ہوگا بلکہ صرف ایک کامیاب عہدہ اور ایک عمدہ سوٹ فیا ویلاہ علی فقید الاسلام ویا خیباہ للمسلمین۔
مرحوم کو سب سے پہلے میں نے دارالعلوم ندوہ میں دیکھا، غالباً ۱۹۰۳ء یا ۱۹۰۴ء میں، پست قد، فربہ جسم، چھوٹی گردن، کچی پکی لمبی داڑھی، سرگھٹا ہوا اور سر پر ایک ترکی...
The Quran is the last book of Allah. The Quran was revealed in Arabic. The Qur'an was not revealed only to the Arabs. This book has been published to guide all Human beings. There for, translation of the Quran is necessary for non-Arabs. The translation of the Quran was started in the beginning of Urdu language. So far there have been many translations of the Holy Quran in Urdu . I have compared Allama Saeedi's translation of the Qur'an with other translations in this article. I have proved in this article that their translation is an extension of the Quran, the Barelvi school. Their translation is often matched by professional translation in many places. Barelvi School has original (genin), translation, Quran, Maulana Ahmad Raza Khan Barelvi and Allama Syed Mohammad Kachochvi. This work of mine is unique in its investigation of Allama Ghulam Rasool Saeedi. In my opinion, resding the Qur’an is essential for the understanding of the Qur’an in order to understand the Qur’an but also the study of translations that have a distinct identity and they have been the study of our teachers.
Peroxisome-Proliferator Activated Receptors (PPAR-Gs) is ligand based nuclear receptor family which have special role in the IR Syndrome (IRS) pathogenesis, which is a pre-diabetic lesion and have major role in type 2 diabetes mellitus (T2DM) development. The PPAR-Gs act as intracellular receptors which help in the gene’s activation responsible for glucose and metabolism of lipid. These receptors upon activation help in nutrient metabolism by activating intracellular enzymatic pathways and also increase uptake by cells. PPAR-Gs receptors also help in insulin signal transduction, any defects in these receptors lead to Insulin loss which can affect body tissues mainly adipose tissue and skeletal tissue. This study aimed to compare T2DM patients with normal controls and identify PPARG abnormal status in adipose tissues of T2DM patients. Transcription factor assay was carried out on adipose tissue of control and patients to assessed PPARG status in both normal and T2DM patients. Transcription factor assay was done by ELISA on DAS plate reader, to quantify gamma PPARG expression in both controls and T2DM patients. Objectives 1. To determine PPARG receptors status in adipose tissues of patients with T2DM Mellitus and IR and their comparison with the results of normal controls. 2. To carry out statistical tests of correlation betweenT2DMand IRS parameters and determine status of PPARG in both controls and patients. Hypothesis Adipose tissue PPARG receptor values are abnormal in Diabetics as compared to Obese and normal people. Null Hypothesis No difference in Adipose tissue PPARG receptor values between diabetics and Obese and normal people Methodology Duration This study was conducted for two years during 2012 to 2014. Setting Current study comprised the subjects presenting diabetes and under treatment in Surgery unit of Ayub Teaching Hospital (ATH) Abbottabad. Biochemical analyses were carried out Ayub Medical College (AMC) Abbottabad in its Chemical Pathology Department, and Biochemistry Department, Hazara University Mansehra. Sample Size Sum of 105 patients were recruited in this study. The criteria was a) T2DM subjects of age groups 40 – 65 years were included. b) Sex and age matched obese people non diabetic taken as obese controls. c) Sex and age matched normal subjects, i.e., without diabetes or obesity, considered as normal controls. Methods Based on selection criteria subjects were selected attending the surgical ward of the Ayub Teaching Hospital Abbottabad. All the information from subjects about their past and present health status, diseases status and health statuswere recorded on Performa according to standard criteria. Transcription Factor Assay on ELISA Technique on PPAR-G was done from nuclear extract of Subjects adipose tissue by using standard protocols, and then stored under appropriate conditions as given.