مولوی عبدالحمید ندوی
یہ سطور ابھی پریس نہیں گئی تھیں کہ مولوی عبدالحمید ندوی کے انتقال کی خبر ملی، وہ بارہ بنکی کے ایک گاؤں جیسکھ پور کے رہنے والے تھے، بڑے مخلص، حق پسند اور بہی خواہ خلق تھے، ۱۹۱۹ء میں ندوہ میں داخل ہوئے، تحریک خلافت شباب پر تھی، حمید صاحب بھی اس سے متاثر ہوئے، اس کی وجہ سے سادگی طبیعت ثانیہ بن گئی، مولانا عبدالرحمن نگرامی کی صحبت نے ان کے اندر ندوہ کی محبت اور خاموش خدمت کا جذبہ پیدا کیا، تعلیم سے فراغت کے بعد قیام زیادہ تر وطن ہی میں رہا، لیکن ندوہ برابر آتے جاتے رہتے تھے، دوستوں کے اصرار کئی برس تک بھٹکل میں تعلیمی خدمت انجام دی، ان کے مخلص شاگردوں نے اس کام کو آگے بڑھایا اور ایک بڑا تعلیمی مرکز قائم ہوگیا، عرصہ سے دل کے مریض تھے، رمضان میں ندوہ آئے، مولانا ابوالحسن علی سے ملنے رائے بریلی جانے کا ارادہ تھا، دفعتہ دل کا دورہ پڑا اور تھوڑی دیر میں جان جان آفریں کے سپرد کردی، اﷲ تعالیٰ ان کی مغفرت فرمائے اور ان کے صاحبزادہ مولوی عبدالرشید ندوی اور دوسرے متعلقین کو صبر جمیل عطا فرمائے۔ (عبد السلام قدوائی، ستمبر ۱۹۷۸ء)
The Holy Quran has been compiled in the order of detention; that is, the Holy Prophet himself gave instructions to the Companions about which verse to place and where he completed the Quran in the same order. He included Madani verses in some Macan Surahs, which may be due to the completion of subjects or the merging of similar verses and the continuation of the Quranic verse on which the commentators have different views. Some verses were revealed in Makkah after the Hijrah, but they are present in the Madani Surah according to the present order of detention. Similarly, the verses revealed during the journey, which were revealed in areas far from Madinah, the place of Mina and Arafat, and the journey to Meraj, are the verses of Mecca, even though they were revealed after the migration. The verses that were revealed during the migration were also included in the Macan Surahs and after the migration, you traveled hundreds of miles away from Madinah and the verses that were revealed at these places were Madani or Macan. If they were Madani, then why were they kept in Macan Surahs.
Why was this done and what are the reasons for it?
Is it not such an arrangement to invalidate the inspired Word?
Was it a different order than the inspired one?
Is it not possible to take these verses from the surahs in which these verses were revealed or to place them in other surahs, to spoil the connection of the previous surahs, or to leave their subjects incomplete? The article under discussion will discuss the topics, discussions, introduction of the verses, details, and reasons for placing the verses in their place in the Macan Surahs and the order and contextual context of these verses. An analytical study of the reasons for separation will be presented.
Dengue virus (DENV) infection is a mosquito born infectious disease. Its diagnostic is utmost important for treatment, as the symptoms of disease are quite similar to other diseases. Current pathological diagnostics methods available are reverse transcriptase polymerase chain reaction (RT-PCR) and enzyme linked immunosorbent assay (ELISA). RT-PCR is used to detect the virus itself while ELISA is used to detect non-structural protein-1 (NS1) and antibodies like immunoglobulin-M (IgM) and immunoglobulin-G (IgG). Existing methods e.g. virus isolation, RT-PCR and ELISA have certain disadvantages like more time consuming, false-positive/false-negative results and expensive as compared to Raman spectroscopy. Raman spectroscopic technique provides molecular signatures, minimum running cost and online results. Raman spectra of biological samples combined with a suitable statistical data-mining technique like partial least squares (PLS) regression can be used to devise a new method for diagnosis of DENV infection in human blood sera. In present studies, this technique is successfully applied for the diagnostic of DENV infection based on three steps. A graphical user interface (GUI) was specially designed and its code was developed in MATLAB (Mathworks 2009a) programming language to implement PLS for the presented research work. First step: Raman spectra of ELISA confirmed NS1 positive and negative sera samples are discriminated by PLS regression. Analysis of regression coefficients, which differentiate these groups, shows an increasing trend for phosphatidylinositol, ceramide and amide-III, and a decreasing trend for thiocyanate in the DENV infected serum. Second step: Raman spectra of samples, with known value of ELISA based AI of IgM are discriminated by PLS regression. Analysis of regression coefficients revealed that concentration of asparagine, glutamate, galactosamine etc. were found to increase while concentration of fructose, cholesterol, cellobiose, and arabinose were found to decrease with increasing values of antibody index (AI) of IgM. Third step: Raman spectra of samples, with known value of ELISA based AI of IgG are discriminated by PLS regression. Analysis of regression coefficients revealed that myristic acid, coenzyme-A, alanine etc. were found to increase, while amide III, collagen, proteins, fatty acids, phospholipids and fucose were found to decrease with increasing values of AI of IgG. Raman spectroscopy provides not only the diagnosis of DENV infection, but it also enables the detailed insight of the abnormalities appearing in molecular composition of a sample. Importantly, Raman spectra @ 532 nm excitation were used to investigate the possible use of lactate as biomarker for DENV infection. It was found that spectral difference in healthy and infected samples is due to an elevated level of lactate in DENV infected group.