امین الدین شجاع الدین
خبر آئی کہ مولانا امین الدین شجاع الدین بھی اپنے خالق و مالک حقیقی سے جاملے، یقین نہ آنے کے چند لمحوں کے بعد پھر اسی یقین کا اقرار کرنا پڑا کہ ہم سب اﷲ ہی کے ہیں تو واپس اسی کے جوار رحمت میں جانا ہی ہے۔
وہ ابھی ایسے نہ تھے کہ نام کے ساتھ مرحوم لکھا جائے، خدا جانے کتنی صلاحیتیں تھیں جو اب بھی ظہور کی منتظر تھیں، ان کا نام اچانک تعمیر حیات اور بانگ حرا کے صفحات پر دلکش، پر اثر اور البیلی تحریروں کے ساتھ سامنے آیا، ان کے اداریے نظر شوق کو متوجہ کرتے ، مقبولیت تھی کہ ان کے اداریوں کا ایک مجموعہ نقوش فکرو عمل کے نام سے مرتب ہوا، بھیونڈی کی زمین سے ندوہ کے آسمان تک کا سفر، تیز رفتار بھی رہا اور روشن بھی، کیا خبر تھی کہ یہ خوش درخشیدگی، شعلہ مستعجل کی مبتدا تھی، آخری ملاقات کب ہوئی یاد نہیں، لیکن ان کا تبسم اور محبت کی آنچ سے گداز ہاتھوں کا گرم جوش مصافحہ ضرور یاد ہے، وفیاتی مضامین کا مجموعہ’’ملنے کے نہیں نایاب ہیں ہمــ‘‘ عنایت کیا، ابھی معارف میں اس کے ذکر کی فرصت بھی نہیں ملی کہ وہ خود اس کتاب کا عنوان بن گئے، حضرت مولانا سید ابوالحسن علی ندویؒ سے سالک رام تک خدا جانے دل کی دنیا میں آ باد کیسے کیسے مکینوں کا نوحہ کہنے والے نگری نگری پھیرا لگاکر وہ اپنے سفر کی منزل پہنچ گئے، پس کارواں سخنوری کے ایسے نقوش قائم کرتے ہوئے جن کی چمک میں خون جگر کی آفرینش ہے، یہ نقوش تابند ہ رہیں گے اور کبھی کبھی دبے الفاظ میں یہ بھی کہہ جائیں گے کہ
کیا تیرا بگڑتا جو نہ مرتا کوئی دن اور
ندوہ کے ساتھ دارالمصنفین کے...
Many people propagate about the Islamic Hudūd i.e. Punish against crimes stated in the Holy Quran. They are of the view that the Islamic Hudūd punishments are more severe, cruel a brutal. Although it a propaganda against Islam. This negative propaganda is an obstacle, hindrance in the way of enforcement of Hudūd. If the Islamic Hudūd are compared with the other Religions, punishments for different crimes, which have been mentioned in their books and Religious history, they are either similar or more sever and brutal than Islamic Hudūd, i.e. Punishment. It show that more sever & cruel punishments against crimes were present in heavenly and man-made Religious before Islam. The research under consideration is about the comparison and contrast between Islamic punishments and the punishments present the international or worldly Religions so that it may be cleared to the whole world that only Islam is a Religion in the world that no other Religion can compete regarding prevention of crimes. It will highlight the sublimity and loftiness of Islam and also make it clear the fact of hollow, attractive slogans of the present modern time.
Thermal pressure alters the normal body homeostasis and cause rigorous injurious sound effects
on production of cattles. Dairy cattles are extra responsive to high temperature as they spawn
further energy expanded rate and this matter grasp particular consideration when the entire
picture of inclusive warm up is measured around the globe. Heat fright proteins are ever-present,
highly conserved proteins that cooperate a significant task in cell endurance through unusual
stresses. The present study was undertaken to assess peculiar relevance of HSP70 gene with heat
tolerance ability in Red Sindhi (Bos indicus), tropically evolved breed of Pakistan. The
aspiration of this study was to explore and portray the heat shock proteins gene diversity in
coding region of Red Sindhi cattle to understand their thermotolerance under hot conditions
using Polymerase Chain Reaction (PCR). The complete coding region of HSP70 is 1926bp long
without any intron, programming a protein of 641 amino acids located on chromosome No.23,
with predicted molecular weight (Mw) of 70,190.56 kDa. The functional parts of HSP70 protein
consist of an amino-terminal or N-terminal 44kDa ATPase domain (amino acid residues 1-386),
18kDa domain is peptide binding (a.a 384-543) and highly conserved 10kDa Carboxyl or
C-terminal domain (residues 542-640) in all eukaryotes. The phylogenetic examination of
mammalian HSP70 gene indicated that Red sindhi has showed (99.79 to 99.48%) homology
with Bos taurus, Bubalus bubalus and Capra hircus while least similar relationship was
observed with Canis lupus that was 86.34%. The results express that nucleotide as well as
deduced amino acid order was greatly preserved. Comparative sequence analysis of Red sindhi
HSP70 gene revealed a total of 14 single nucleotide polymorphic sites, of these 5 were
non-synonymous (C14T, G970T, C1469T, A1535T, G1560T) caused change in amino acid
sequence while 9 were synonymous. In non-synonymous SNPs the 1
one was reported and four
novel type. These 9 mutations caused no change in amino acid. 8 out of 14 were transition type
in which purines were replaced by just purines and pyrimidines replaced by other pyrimidines. 6
types were transversion mutations in which purines replaced by pyrimidines and vice versa. At
protein level, Red sindhi HSP70 gene has showed total 5 amino acid changes and two of five are
in N-terminal domain (M5T, A324S), remaining are in peptide binding domain (A490V,K512M,
Q520H). Probably damaging functional impact of amino acid change is seen in two of expressed
SNPs. These transformations can be worn as molecular genetics pointer to aid assortment for
anti-heat stress cattles. The findings of this study revealed that detected polymorphisms may be
associated with ability of bovine to adapt with tropical and harsh climatic conditions but
additional exploitation still required to draw the ending about molecular roots of thermotolerant
cattles.