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Home > سلسلہ چشتیہ نظامیہ کے لٹریچر کا جائزہ: خواجہ معین الدین چشتی سے کلیم اللہ جہاں آبادی تک۔

سلسلہ چشتیہ نظامیہ کے لٹریچر کا جائزہ: خواجہ معین الدین چشتی سے کلیم اللہ جہاں آبادی تک۔

Thesis Info

Author

خالدہ چودھری

Supervisor

غلام شمس الرحمٰن

Program

MA

Institute

Bahauddin Zakariya University

City

ملتان

Degree Starting Year

2005

Language

Urdu

Keywords

شخصیات

Added

2023-02-16 17:15:59

Modified

2023-02-17 21:08:06

ARI ID

1676731952141

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غلط فہمی دا نتیجہ

غلط فہمی دا نتیجہ

اک دفعہ دا ذکر اے کہ کسے جنگل وچ دو بکریاں رہندیاں سن۔ جنہاں دا آپس وچ بہت پیار سی تے اوہ اک دوجے اتے اعتبار وی کردیاں سن۔ دونویں جنگل دے پھل تے گھاہ کھا کے بہت موٹیاں تے سوہنیاں ہو گئیاں سن۔ جدوں اوہناں وچوں کسے اک اتے وی کوئی مصیبت آندی تاں اوہ رل کے اک دوسرے دی مدد کر دیاں تے انج اوہ مصیبت کولوں جان چھڑا لیندیاں سن۔ روز اوہ چرن لئی دوسرے جنگل جاندیاں۔ رستے وچ اوہناں نوں ہر ویلے خطرہ رہندا سی۔ کیوں جے بہت سارے خون خوار جانور اوہناں نوں کھانا چاہندے سن۔ پر اوہناں دے آپسی پیار پاروں اوہ حملے دی جرأت نئیں سی کردے، جویں کہ اک وار شیر نے اک بکری اتے حملہ کیتا۔ دوسری نے شیر دے ڈھڈ وچ سنگھ مارے تے شیر نوں زخمی کر دتا۔ شیر زخمی حالت وچوں اوتھوں دوڑ گیا۔ شیر دی سارے جانوراں سامنے بہت بے عزتی ہوئی تے اوہنے بے عزتی دا بدلہ لین لئی سوچنا شروع کیتا۔ پر کوئی وی حل اوس دے ذہن وچ نہ آیا۔

اک دن شیر نے لومڑی نوں سدیا تے اپنے پروگرام بارے اوس کولوں رائے منگی۔ لومڑی نے آکھیا کہ جدوں تائیں اوہناں وچکار غلط فہمی پیدا نہ کیتی جاوے۔ ایہہ کم ممکن نئیں ہونا۔ غلط فہمی پیدا کرن دا ذمہ اوس چکیا تے اوہ بکریاں ول چلے گئی۔

اک بکری چر رہی سی تے دوجی پانی پین ندی اتے گئی سی۔ اوس نے ایس موقع توں فائدہ چکدے ہوئے پہلاں بکری دی خیر خیریت پچھی تے بعد وچ آکھیا کہ اوس نوں پیاس نئیں سی لگی، اوہ بہانہ بنا کے تیرے کول جان چھڑوا کے گئی تاں جے شیر تیرے اتے حملہ کرے تے اوس دی جان بچی...

البنوك الإسلامية ودورها في الاقتصاد التركي

Within the global financial system, Islamic banks have a small but growing share, and today they have become an integral part of the global financial system. Islamic banks in the world have been operating according to interest-free financing techniques, which are mainly developed on sharing of profits and losses in accordance with the difference principles between purchase and sale. However, the presentation of financial products in Turkey is conducted by ‘participation banks’ operating according to Islamic rules. Participation banks play a vital role in economic development by gaining the unused funds to the economy. This study will examine the performance of the participation banks operating in Turkey and their increasing share in the Turkish finance sector will be assessed. The work sheet will contain three demands: First: Islamic banks and the difference between them and the definition of riba-based banks. Second: The history of Islamic banks in Turkey. Third: The role of Islamic banks in the sustainable development of the Turkish economy.

Suppression of Seizure-Induced Increased Expression of Jak/Stat Signaling in Kindling Model of Epileptogenesis Using Isoxylitones [E/Z]

Epilepsy is a chronic neurologic disorder result from electrical disturbances that lead to abnormal discharge of neurons within the CNS. This discharge produced unprovoked and recurrent seizures which alter the normal brain functions. These functional alterations often give rise to behavioral abnormalities, with devastating effect on the patients and their families. To date, major advancement has been done in the treatment of epilepsy, but still, epilepsy is a great challenge in the medicine field which pays attention towards the invention of new and more potential AEDs. Regardless of latest advancement in the epilepsy, an about one third population is unresponsive. So, the proposed underlying mechanism of transfer of normal brain to epileptic is still unanswered and this highlight to identify new targets of drug treatement. For it , we established the seizure threshold, and used exogenous antiepileptogenic mediator i.e., isoxylitones [E/Z] to evaluate if this can control the over expressed JAK-STAT pathway in the model of epileptogenesis and finally discuss the attempts to halt the process of epileptogenesis by regulating the JAK-STAT pathway. From ancient time to present, there is a strong history of usage of plants and their extracts in the treatment of different neurological disorders. Delphinium denudatum is a medicinal plant of Himalayas and Kashmir, locally called Jadwar. This plant is claimed by many local practitioners to be used in seizure treatment. The novel antiepileptic compound ISO[E/Z] was initially isolated from the same plant and later it was synthesized. Previous studies in our lab already reported that ISO[E/Z] have potent antiepileptic effect. It is able to reduce the seizures in kindling model of epileptogenesis. This inhibition of seizure was further confirmed by modulation of BDNF, cfos and through blockage of sodium channel. In current study, we explored the effect of ISO[E/Z] at the molecular and cellular level by targeting JAK-STAT pathway, that is involved in the epileptogenesis process. The ISO[E/Z] was re-synthesized by our collaborator’s team, X therefore in order to validate and standardize the fresh supply of ISO[E/Z], we re-tested the compound both in acute and chronic seizure model. This step was carried out in order to keep compliance with previous findings. For present study, we choose JAK-1, JAK-3, STAT-2 and STAT-5a isoforms of JAK-STAT pathway due to their importance and involvement in the process of epileptogenesis. We found over expression of mRNA and protein of the above mentioned biomarkers in both cortex and hippocampus of untreated PTZ-kindled group. However, the treatment of ISO[E/Z] was able to reduced the JAK-1, JAK-3, STAT-2 and STAT5a expression. These findings suggest that ISO[E/Z] can halt the epileptogenesis progression by interrupting the underlying functional changes at molecular level. Moreover, our findings also validate our previous studies on isoxylitones with a promising compliance. In the light of all these observations, it can be said that isoxylitones in future would be a potential AED in the treatment of refractory epilepsy. At this stage, promising data support the further development of ISO[E/Z] as an inhibitor of JAK-STAT pathway and this strategy is expected to be valuable to modify or prevent the epilepsy. We think, for an adequate control, it is necessary to used a combination of drugs that hit the multiple targets which are the main players underlying epileptogenesis.