عیدی
جب لوگ آسمان کی وسعتوں میں
ایک خم دار دھندلی سی لکیر تلاش کر رہے تھے
جو سب کے لیے باعث ِ مسرت تھی
مگر کسے خبر تھی
وہ شام میرے لیے غموں کے طوفان لانے والی ہے
اس لکیر کو دیکھتے ہوئے
میرے تصور میں بھی ایک نقطہ سا پھیلنے لگا
جو ایک مانوس صورت کا روپ دھار رہا تھا
چند قیمتی اذیت دہ لمحات میں ڈھلتی صورت
Aims of Study: From last one decade, advancements in formats of cricket demand agility in the players so that they can play in better way without injury. The aim of this study was to determine which dose of plyometric training is effective to enhance agility in cricket players.
Methodology: Randomized Controlled Trial was registered in US clinical Trial registry (NCT04350385). 40 cricket players were recruited in study, out of which n=20 players were placed in experimental group and n=20 players were in control group. Assessments were taken as baseline and after third week and on sixth week through Illinois Agility Run test, T test and Vertical jump test. Data analysis was done through SPSS version 23. Independent t test was used for between group analysis and paired t test for within group.
Results: Group comparison through T-agility and Illinois test shows significant effect in experimental group (p>0.009). Post intervention Mean±SD of vertical jump test in experimental group was 31.90±2.55 with significant effect (p=0.001).
Limitation and Future Implications: This study can be done on both genders. Players can improve their performance by working on plyometric training and agility.
Originality: This was original work and never published before.
Conclusion: It is concluded from this study that plyometric training is effective in improving agility of the cricket players. Players can improve their performance by working on plyometric training and agility.
A chemical library of N, N''-Disubstituted thioureas have been derived from substituted aromatic carboxylic acids and two types of combinatorial strategies have been employed for the construction of chemical library. For high throughput screening of components of the chemical library, solution-phase pool syntheses have been exercised, where each pool consists of four components. All the members of chemical library have also been synthesized by using a parallel mode of solution-phase combinatorial synthesis for the purpose of lead screening/identification, testing, characterization and for assembling of Cu(I), Cu(II) & Pd(II) metal complexes. Copper(I) (1A-19A, 1B-19B, 1C-19C& 1F) and palladium(II) [(1E-14E)] complexes of N, N''-disubstituted thioureas have only been synthesized with some selected thioureas from sub-library-1 and Cu(II) complexes (1D-6D) with isoureas (1-6), prepared from the thioureas derived from benzoic acid. All the thioureas (1a-40a, 1b-40b, 1c-40c, 1d-40d, 1e-40e, 1f-40f & 1g-40g) and complexes have been characterized by elemental analyses, FT-IR, 1 H & 13 C NMR spectroscopy, mass spectrometry and single crystal XRD. The stability of the Cu(I) complexes in the test medium has been confirmed by cyclic voltammetric studies. The products of pool syntheses (pools 1-40) have been characterized by mass spectrometry and GC-MS (gas chromatograph coupled with mass spectrometer) techniques. In all the Cu(I) and Pd(II) complexes, neutral N, N′-disubstituted thiourea ligands have been coordinated to the metal atom through the sulphur atom in a terminal mode except (1F), where the deprotonation of NH group of the thiourea ligand has facilitated the bonding of copper atom through N and S. The isoureas (1-6) show bidentate behavior in Cu(II) complexes having square planar geometry (1D-6D). The thioureas have also been examined for their fungicidal properties and these show significant activity against various fungi strains and low phytotoxicity for the representative monocot plant species. The complexes have been screened for their in vitro cytotoxicity in human cell lines carcinomas A498 (renal), EVSA-T (breast), H226 (lung), IGROV (ovarian), M19 (melanoma-skin), MCF-7 (breast) and WIDR (colon). They show a moderate cytotoxicity against these seven human cancer cell lines in comparison to that of the less active standard chemotherapeutic drugs. Biological screening of the synthesized thioureas and their metal complexes for various targets is in progress.