پروفیسر خلیق احمد نظامی کی یاد میں
(پروفیسر اصغر عباسی)
’’نظامی صاحب بلند پایہ عالم اور ملک کے ممتاز مورخ اور دارالمصنفین کے رکن رکین تھے، ان پر بعض مشہور اہل قلم سے جن کو ان سے گہری واقفیت تھی، مضمون لکھنے کی فرمایش کی گئی ہے، اس مضمون میں ان کی زندگی کے ایک خاص پہلو ہی سے گفتگو کی گئی ہے‘‘۔ (ض)
خلیق احمد نظامی صاحب کے نام نامی سے میں علی گڑھ آنے سے پہلے ہی واقف ہوچکا تھا لیکن ملاقات ۱۹۶۸ء میں ہوئی جب راقم الحروف سرسید ہال کا طالب علم تھا اور وہ اس کے پرووسٹ مقرر ہوئے تھے۔
نظامی صاحب متوسط قد کے تھے لیکن ان کا جسم ایسا تھا کہ ہر لباس خواہ ہندوستانی ہو یا انگریزی ان پر خوب پھبتا تھا، ان کا رنگ گندمی تھا جس کی وجہ سے ان کے سفید بالوں کی جو قدرے لمبائی لیے ہوئے تھے سپیدی کا احساس بڑھ جاتا تھا۔ ان کی آنکھیں بڑی نہیں تھیں لیکن نہایت روشن تھیں جن میں ایک خاص چمک تھی، ان کے چہرے سے رعب عیاں ہوتا تھا لیکن خوف بالکل نہیں معلوم ہوتا تھا۔
نظامی صاحب مجسم علم تو تھے ہی لیکن ان کے سرتاپا عمل ہونے کا عقدہ اس وقت کھلا جب انہوں نے پہلی بار یونیورسٹی میں انتظامی عہدہ سنبھالا اور سرسید ہال میں پرووسٹ ہوکر آئے، ان کے زمانے میں ہال نے بڑی ترقی کی۔ میں اس کا عینی شاہد ہوں کہ وہ ہال کے دفتر میں حساب کا ایک ایک رجسٹر دیکھتے، مددگاروں کو انتظامات کی ایک ایک جزئی باتیں سمجھاتے انہیں راستہ بھی دکھاتے اور ایک ایک کام کی تاکید بھی کرتے اس کا نتیجہ یہ ہوا کہ ہال کے درد و دیوار سے لے کر اس کے سبزہ زار تک سب سرسبز اور شاداب ہوگئے۔ دراصل ہال کی...
This article encompassed the Holy Prophet's (ﷺ) best war strategy in the conquest of Makkah and its relevance to the Modern society. The purpose of this article was to highlight the war strategy of Holy Prophet (ﷺ) in the conquest of Makkah. His strategy provided the noble example for warfare in modern world. The method used for research was historical. The review of literature revealed that the war, humanity for love the showed (صلى الله عليه وسلم) Muhammad Prophet of strategies concern for the safety of the lives and avoided bloodshed as far as possible. Because of his noble strategies, Makkan tribes surrendered without any resistance in front of the army of Islam. Consequently, (صلى الله عليه وسلم) Prophet Holy the and idolatry from freed became Makkah conquered the last and the most solid stronghold of the enemy. In Modern era, Muslim faced so many war problems. Through the war war the learn can commanders military, (صلى الله عليه وسلم) Prophet Holy of strategies ethics and overcome their problems. It is recommended to Muslim army that they should take guidance from the war strategy of Prophet pressure psychological putting by enemy defeat and (صلى الله عليه وسلم) Muhammad upon them.
Diabetes Mellitus (DM) is an advanced and chronic endocrine disorder characterized by insufficiency of insulin secretion from pancreatic beta cells or of insulin resistance in peripheral tissues such as liver, adipose tissues and skeletal muscles. Glucokinase (ATP: D-glucose-6-phosphotransferase; GCK), initiates glycolysis and acts as a glucose sensor and metabolic signal producer in liver and pancreas. The present study investigated differences in allelic frequencies between 60 individual diabetics with typeII and 60 healthy controls. Clinical manifestations identified, GCK gene was selected analyzed data were compared to RFLP of the glucokinase gene and results confirmed about mutation. There were also significant differences (P<0.0001) in glycation levels (0.90, 0.4838mole/mole), random blood sugar (348.8, 105.8 mg/dl), cholesterol levels (235.3, 161.8 mg/dl), low density lipoprotein in diabetic subjects (155.3, 28.46 mg/dl) and in healthy donors. GCK gene mutations were found in 70% of the patients while 30% are non-mutated. The basic aim of this study is to understand the mechanism and genes which are responsible for the prevalence of diabetes and to investigate new trends and methods used for the treatment of this disease. A hereditary variation of a gene is mentioned in this study, it is a change in a nucleotide sequence with an addition, deletion, or investment of a nucleotide sequence. In particular, genetic variation in a gene includes a single nucleotide polymorphism. Samples show the mutation insertion, deletion and insertion/deletion. PCR-sequencing showed qualitative differences in diabetic patients in comparison to non-diabetics. Glucokinase is the most important component in glucose detection of pancreatic islet beta cells in diabetes because glucokinase mutations can be one of the most common single gene disorders described. It is known that a genetic variation of a human glucokinase gene, including a point mutation, causes MODY, concentration of plasma glucose increased and it is supposed to be the cause of diabetes of the present study subjects. The main aspects of the work were designed to investigate immunological cross-reactivity between viral antigens and pancreas-specific self-antigens. This is to investigate, hypothesis that type1 diabetes may be triggered following infection with commonly occurring viruses such as coxsackie B, rotavirus, rubella, mumps and cytomegalovirus. The ANOVA of peripheral blood CD3+ T cells in healthy controls expresses higher level (1.475 ± 0.2930), than the diabetic patients (0.685±0.0927). CD14+ T-cell on monocyte1 frequency were analysed by flow-cytometry in the same Diabetes Mellitus patients expressing the higher level in healthy control (10.79±9.225) when compared to diabetic subjects (2.615±0.5850) and CD14+ on monocyte2 in healthy subjects’ level is higher (11.41±9.925) as compared to the diabetes (2.415±1.575). B-Cell marker CD19+ in healthy donors show higher significant level (5.085±5.055) and in diabetic subjects it is comparatively lowers (3.615±1.825). In conclusion, this study proved that oxidative stress increases the production of ROS causes the hyperglycaemic control stimulates the failure of different cells like lymphocytes subsets ultimate causes the cell death.