قرآن پاک کی روشنی میں اسلاموفوبیا کی سدباب کے لئے حکمت عملی

In Western, countries there is a great fear of Islam and Muslims leading to a great hatred which in turn makes them think that Islam is a religion of violence that it allows the massive killing of people. After the incident of 9/11, Islamophobia has taken another turn. In this regard, it is the utmost duty of every Muslim to find the solution to this problem collectively as well as individually. It is therefore necessary, to think of a solution which favors the teachings of Islam without harming the humanity. It is a pressing need of the day that the true picture of Islam be brought forth through practice upon Shariah. We as muslims should play our role in changing the perception of our religion as the religion of ‘peace’ and preserver of humanity.

Structural and Functional Studies on Proteins and Peptides of Cuminum Cyminum and Other Species

Ajwain (Trachyspermum ammi) belongs to the family Umbelliferae, is commonly used in traditional, and folk medicine due to its carminative, stimulant, antiseptic, diuretic, antihypertensive, and hepatoprotective activities. Non-specific lipid transfer proteins (nsLTPs) reported from various plants are known to be involved in transferring lipids between membranes and in plants defense response. Here, we describe the complete primary structure of a monomeric non-specific lipid transfer protein 1 (nsLTP1), with molecular weight of 9.66 kDa, from ajwain seeds. The nsLTP1 has been purified by combination of chromatographic techniques, and further characterized by mass spectrometry, and Edman degradation. The ajwain nsLTP1 comprises of 91 amino acids, with eight conserved cysteine residues. The amino acid sequence based predicted 3D structure is composed of four α-helices stabilized by four disulfide bonds, and a C-terminal tail. The predicted model was verified by using different computational tools; i.e. ERRAT, verify 3D web server, and PROCHECK. The docking of ajwain nsLTP1 with ligands; myristic acid (MYR), and oleic acid (OLE) was performed, and MD (Molecular Dynamics) simulation was used to validate the docking results. The findings suggested that amino acids; Leu11, Leu12, Ala55, Ala 56, Val15, Tyr59, and Leu62 are pivotal for the binding of lipid molecules with ajwain nsLTP1.