سیرت نگاری کی مشرقی و مغربی روایت: منتخب مصنفین کا تقابلی جائزہ

In the past, mode of Sirah writing was historical and descriptive but during the 19th century, this trend has been changed to the empirical research methodology. Due to religious devotion, unauthentic narrations were not judged and had been quoted constantly in Sirah literature on which orientalists laid the foundation of their objections. In response, various books are produced introducing argumentative, logical and scholarly way of writing to defend “Sirah of Prophet (PBUH)”. Question is what are the motives and causes which have changed classical trend of Sirah writing and what are its consequences? In this paper, a comparative analysis will be taken of books of Eastern Muslim scholars; Rehmatullah Keranwi, Syed Ahmad Khan, Karam Shah Alazhari, Shibli Noumani, Sana ullah Amertasri as well as Western Muslim scholars Mohammad Hussain Haykel, Hameed ullah, and Mohammad Asad. This paper will elaborate the difference between both of their research methodology and its effect in the field of Sirah writing and will be helpful for researchers.  

Acinetobacter Infections: A Retrospective Study to Determine in – Hospital Mortality Rate and Clinical Factors Associated With Mortality

Background: Acinetobacter infections are increasingly being recognized as a cause for significant in – hospital morbidity and mortality worldwide. Increasingly multi – drug resistant strains of Acinetobacter are being isolated, increasing the burden on healthcare resources. Our objectives were to determine the outcomes and clinical factors related to outcomes of Acinetobacter infections at the Aga Khan University Hospital. Methods: A retrospective study of Acinetobacter infections (from any site) was conducted. Patient records were used to gather relevant clinical information. The collected data was tabulated and analysed for any significant differences in demographic or clinical variables. The Pearson Chi squared test was used for categorical variables and the Student’s t-test was used for continuous variables. Significant factors were entered into a logistic regression model. Survival analysis using Kaplan Meier and log rank tests were performed to assess for significance between the different subgroups. Results: Between 2010 and 2017, 80 infections were identified (32 VAP, 24 BSI, 13 skin and soft tissue, 9 pneumonia and 2 UTI) from 204 positive cultures. Thirty six (45%) of the infected patients died. The mean length of stay for the entire cohort was 35.5 days. Diabetes was the most common comorbid condition and Carbapenems were the most frequently prescribed antibiotic prior to infection. Sixty nine (86.25 %) of the Acinetobacter isolates were MDR. The Mean SOFA score, presence of a CVC, Mean age and COPD were found to be significantly different between the two survival groups. Using logistic regression models, the mean SOFA score was significantly associated with mortality. Conclusion: The mortality from Acinetobacter infections at our institution was 45 %. The most common infection was VAPs. The mean SOFA score, age, COPD and CVC were significant factors between the two survival groups, however, only the mean SOFA score was a predictor of death.