Faith in God is the core cultivation of most of the religions. Especially in Abrahamic religions, this faith is fundamental principle. For centuries, thought-provoking debates regarding the existence of God have been part of philosophy and other scientific fields. Although there are undoubtedly several confirmations of God's existence in the revealed writings, it is asserted that the Holy Qur'an contains a thorough discussion of this phenomenon. Dr. Stephen Meyer is one of the most prominent scientists who has offered various scientific arguments in support of God's existence. The target and goal of the current work is, a comparative analysis of Meyer's and the Quranic arguments. This research develops insight for better grasp of science-related arguments of Qur’an and a legitimized scientist as the associations and disassociations between both sets of arguments are encompassed. The current research suggested that Qur'an takes a more general approach while Meyer takes a more scientifically specific approach which also discusses the details. The Qur'anic knowledge is for everyone, while Mayer's arguments are only for those who understand science.