This study argues that political entertainment and TV comedy is getting popularity among TV audience. These shows are deliberating and presenting the political culture of Pakistan in a witty and sarcastic way. Usage of Humor, Satire and Parody in these shows may provide audience with the various interpretations of political issues, political parties and their leadership. Therefore, present study is also aimed at exploring these theoretical underpinnings in response to political comedy shows. Six issues were selected to study the issues’ importance, treatment, framing and priming at the production end of TV comedy content and viewers’ consumption end. Mixed method approach was applied employing the content analysis of comedy programs during elections and survey of viewers of comedy for data collection. Framing, priming and agenda setting theories have been applied in the present research .Results of the study indicate that political issues are frequently discussed and significantly associated with certain frames that ultimately treat the issues giving them slants towards certain political parties. On the other hand, viewers prefer to watch comedy and are aware of different shows, formats and segments of comedy. Their exposure to comedy also show that they have opinion about the importance of issues, frames and perception about the parties. Taking both content and survey results, Correlation was found for issues’ importance, frames, slants/ perception of political parties majorly. However, crosstabs showed some difference of scores on issues, frames and priming results. Although viewers are relying on TV comedy but they also negotiate with issues, frames and slants presented and primed in TV comedy.