خلاصہ بحث
قرآن مجید اللہ تعالیٰ کا کلام ہے جس میں مختلف انداز واسالیب کا ذکر کیا گیا ہے تاکہ انسانی نفوس پر کلام گراں نہ گذرے۔مختلف اسالیبِ قرآنی میں سے ایک اسلوب اسلوب ِاستفہام ہے۔ قرآن مجید میں اللہ تعالیٰ اپنے بندوں سے مختلف سوال فرماتے ہیں جو کہ مختلف نوعیت کے حامل ہوتے ہیں۔ ان سوالات کی آیات کو آیاتِ استفہام کہا جاتا ہے ، جن میں کئی ایک مصلحتیں پوشیدہ ہیں ۔کہیں انسان کو ڈرانے کے لئے سوال ہے تو کہیں باطل کا رد کرنے کے لئے ،کہیں بغرض توبیخ کے ہے تو کہیں تشویق کی غرض سے، الغرض استفہامی اسلوب کو متعدد مقامات پر متعدد مقاصد کیلئے لایا گیا ہے۔فصل ہذا میں استفہام کے لغوی واصطلاحی معنی بیان کرتے ہوئے ادوات استفہام کی وضاحت کی گئ ہے اور قرآن کا استفہامیہ اسلوب بیان کیا گیا ہے آیات استفہام کی تعداد اور جن سورتوں میں یہ وارد ہوئیں ہیں انکی تعداد بیان کی گئی ہے اور تفاسیر کی روشنی میں آیات استفہام کا تحقیقی جائزہ پیش کیا گیا ہے۔قرآن مجید میں کل نو(۹) ادواتِ استفہام کو ذکر کرتے ہوئے قرآن مجید کی چھیانوے (۹۶) سورتوں میں کل آٹھ سو چونسٹھ (۸۶۴) آیات میں استفہامی اندازِ بیان کو استعمال کیا گیا ہے۔
Globally, peptic ulcer is a disease that is very common in an adult population with 10% prevalence. Patients with H. Pylori infection has 3 to 4 folds higher risk of getting peptic ulcer. Objective: To find out the determinants of Peptic ulcer among the patients visiting Services Hospital LahoreMethods: A Cross sectional study was carried out. Patients were selected through non-probability convenient sampling technique from Services Hospital, Lahore. Patients were assessed through pre-tested questionnaire. SPSS version 21.0 was used for analysis of data. The study was carried out at Medical departments of Services Hospitals, Lahore during Dec-2017 to March-2018Results: The prevalence of peptic ulcer was higher in males i.e. 68%. 41% patients were 36-45 years of age, 63% patients were from urban areas, 40% of patients were overweight, 32% patients were secondary educated and 75% patients were having no knowledge about peptic ulcer. There was significant association of gender with consumption of fried food items and smokingConclusions: Study concluded that, male gender, low educational status, work pressure, smoking, addiction of pain killers and intake of fried food items were the risk factors of peptic ulcer.
Myocardial infarction (MI) was induced in rabbits by isoproterenol (85 mg/Kg body wt.). Five indigenous plants Allium sativum, Allium cepa, Zingiber officinale, Terminalia arjuna and Moringa oleifera were selected to prepare 64 possible combinations. Native as well as gemmomodified plant extracts of selected parts of Allium sativum, Allium cepa, Zingiber officinale, Terminalia arjuna and Moringa oleifera were prepared and combined to make treatment combinations against isoproterenol induced MI. Both the preventive & curative ways of treatment were employed on different treatment groups prepared by placing 140 healthy rabbits in specific groups. The effects of different plant combinations were assessed through the serum level of biochemical markers at calculated time intervals. Plant combinations decreased the isoproterenol induced rise in biomarkers as CK-MB, LDH, ALT, AST, ALP, total cholesterol, triglycerides, glucose, urea and uric acid to the level of these parameters in C1 and C2 control groups as compared to C3 (isoproterenol group). Sharp decrease in the level of enzymes/parameters was observed in class III (GP: combination of gemmo extracts used in preventive way) followed by class I (GC: combination of gemmomodified extracts used in curative way). Out of 64 combinations of five plants, 16GP (gemmomodified combination of Allium sativum, Allium cepa, Zingiber officinale, Terminalia arjuna and Moringa oleifera used in preventive mode) gave the excellent cardioprotective potential followed by 16GC (gemmomodified combination of Allium sativum, Allium cepa, Zingiber officinale, Terminalia arjuna and Moringa oleifera used in curative mode) throughout the study. Findings were further strengthened by gross and histopathological studies. Isoproterenol also affected the organs other than heart as liver, kidney and lungs. There was no genotoxicity imposed by any of the combinations as biomonitored by Comet Assay. GC-MS analysis revealed the presence of 4-(4-hydroxy-3methoxyphenyl)-2-butanone, n- Hexadecanoic acid and oleic acid as actively curing constituents with antioxidant and cardioprotective potential in 16G. The 16G (gemmomodified combination of Allium sativum, Allium cepa, Zingiber officinale, Terminalia arjuna and Moringa oleifera) was further applied on human volunteers suffering from chronic tachycardia and hypertension. There was a significant decrease in pulse rate and blood pressure in the patients who were treated with 16G in combination with inderal (inderal+16G) as compared to patients who were treated with inderal and 16G separately.