64. Al-Taghabun/Mutual Neglect
I/We begin by the Blessed Name of Allah
The Immensely Merciful to all, The Infinitely Compassionate to everyone.
64:01
a. Whatever is within the celestial realm the terrestrial world is Glorifying Allah – The One and Only God.
b. For HIM is The Sovereignty, and for HIM is The Praise and Gratitude.
c. And HE Manifests Sovereignty over all existence.
64:02
a. It is HE WHO created you as human species starting from Adam and Eve,
b. then, among you, some would be a disbeliever and among you some would be a believer.
c. And Allah Watches over whatever you do: good and evil.
64:03
a. HE created the celestial realm the terrestrial world with truth: meaningfully and for a
definite purpose,
b. and gave you shape and shaped you well,
c. and made the human form to be the best of forms.
d. And to HIM is going to be your return: starting with death and then upon the resurrection.
64:04
a. HE Knows whatever is within the celestial realm and the terrestrial world,
b. and HE knows whatever you hide of your motives and deeds as well as whatever you disclose of them.
c. And Allah is All-Aware of whatever is within the hearts.
64:05
a. Has not the account of those come to you who disbelieved before you in the Missions and the Messages of their Messengers?
b. So they tasted the evil consequences of what they did, and for them was a painful punishment.
64:06
a. That was so because their Messengers came to them with Clear Messages, but they would
mockingly say:
b. What!
c....
Artisanal fishing is carried out in the coastal villages of Karachi. Through centuries, these fishing villages have maintained their traditional practices of fishing. Shams Pir Island is in vicinity of Karachi coast. The main occupation of islanders is artisanal fishing which is extremely threatened by various factors. Historically, in coastal communities of Karachi, women were part of fishing and its related activities. With the decline in traditional fishing methods, females have been withdrawn from fishing work. Implications of this process have been drastic for fishing households such as increased poverty, unemployment, environmental degradation etc. The research is conducted to highlight these problems especially from gender perspective. It is exclusively based on females of Shams Pir Island. Female’s socio-economic conditions, family status, perceptions on different contemporary issues pertaining to the endangered livelihood of their family and its relation with environmental changes is investigated in particular. In total, sixty women representing fishing households, few community leaders and representatives of fisher folk’s NGO were interviewed. The results emphasized the livelihood issues of females and their perceptions on environment and climate change. The vulnerabilities of females in fishing communities have been discussed in detail. ______
In the present study, a series of tri- and diorganotin(IV) carboxylates have been synthe sized by the reaction of tri- and diorganotin(IV) chlorides/oxides with substituted phenylethanoic acids/salts and α-alkyl cinnamic acids/salts in dry toluene under reflux condition for 8-10 h. The ligands used were 4-Methoxyphenylethanoic acid (HL 1 ), 4- Nitrophenylethanoic acid (HL 2 ), 4-Chlorophenylethanoic acid (HL 3 ), 3-Methylphenyl ethanoic acid (HL 4 ), 3-(4-Bromophenyl)-2-ethylacrylic acid (HL 5 ), 3-(4-Bromophenyl) -2-methylacrylic acid (HL 6 ), 3-(4-Chlorophenyl)-2-methylacrylic acid (HL 7 ), 3-(4- Chlorophenyl)-2-ethylacrylic acid (HL 8 ), 3-(4-Nitrophenyl)-2-methylacrylic acid (HL 9 ) and 3-(4-Nitrophenyl)-2-ethylacrylic acid (HL 10 ). The composition, coordination mode of ligands, structural confirmation and geometry assignment of the complexes in solid and in solution states were made by different analytical techniques such as elemental analysis, FT-IR, multinuclear ( 1 H, 13 C and 119 Sn) NMR, mass spectrometry and X-ray single crystal analysis. Based on these results, the ligand appeared to coordinate the Sn atom via COO moiety. The triorganotin(IV) derivatives demonstrate polymeric trigonal bipyramidal geometry in solid state and a monomeric tetrahedral structure in solution. The diorganotin(IV) dicarboxylates have shown a distorted octahedral or skew- trapezoidal geometry in solid state, however, the coordination around Sn change from six to five in solution, in most cases. The interaction of (n-C 4 H 9 ) 3 Sn(IV)L, (CH 3 ) 3 Sn(IV)L, (n-C 4 H 9 ) 2 (IV)SnL 2 and (C 2 H 5 ) 2 Sn(IV)L 2 (where L = 4-nitrophenylethanoate) with DNA was investigated by cyclic voltammetry (CV). The positive peak potential shift in CV evidenced intercalative mode of interaction of these complexes with DNA. The CV results revealed the following increasing order of binding strength: (C 2 H 5 ) 2 Sn(IV)L 2 (8.5 x 10 3 ) < (n-C 4 H 9 ) 2 Sn(IV)L 2 (1.11 x 10 4 ) < (CH 3 ) 3 Sn(IV)L (1.39 x 10 4 ) < (n- C 4 H 9 ) 3 Sn(IV)L (1.46 x 10 4 ) M -1 . The negative values of ∆G designate the spontaneity of complex-DNA binding. Most of the synthesized complexes were screened for their antibacterial and antifungal activities against various medically important bacteria and fungi. The triorganotin(IV) derivatives have strong bactericidal and fungicidal action than diorganotin(IV) complexes with few exceptions. Some of the compounds were found to have antimicrobial activity comparable or even more than reference drugs and may be used as drugs in future. Some complexes have shown higher cytotoxicity(against iiBrine shrimp) than standard drug while only compound 10 was found stronger anticancer agent against human prostate cell lines(PC-3).