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Anti-Hyperlipidemic Effects of Some Herbs Psyllium Husk and Moringa Oleifera in Rabbits Fed With High Fatdiet

Thesis Info

Access Option

External Link

Author

Sabahat Shabbir

Institute

Virtual University of Pakistan

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Subject

Software Engineering

Language

English

Link

http://vspace.vu.edu.pk/detail.aspx?id=315

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676721021803

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Natural dietary modifications are charismatically used as a first line therapy for treating several diseases. The present study was conducted to examine the antihyperlipidemic effect of herbs Psyllium Husk and Moringa oleifera in rabbits fed with high fat diet. A total of (n=30) rabbits were subjected to five treatment groups with (n=6) animals in each group. The Group I-V were kept under different dose administrations. After eight weeks of experimentation, the blood and tissue samples were tested for biochemical and histopathological analysis. Histopathological studies revealed that MO and PH are hepato-protective and nephro-protective as well. The findings were collaborated with the facts that MO and PH exhibited therapeutic properties against serum lipid parameters. The LDL, TC, TG and Glucose levels were suppressed to significant value P=0.05. It was also inferred that MO and PH elevated the concentrations of good cholesterol HDL. It was suggested that both herbs possessed bioactive compounds like antioxidants that are curative and preventive in nature and might be helpful in lowering secondary hyperlipidemia.
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آرتھر ہیورڈ

مسٹر آرتہر ہیورڈ

لندن کے امپرئیل کالج آف سائنس میں مسٹر آرتہر ہیورڈ سائنس سے متعلق ایک تجربہ کرتے کرتے وفات پاگئے، وہ کچھ عرصہ سے فن تصویر کشی (فوٹوگرافی) سے متعلق تجربات میں مشغول تھے، اور آخری تجربہ ایک تاریک کمرہ کے اندر کررہے تھے، کمرہ میں روشنی کا کسی۔۔۔۔ ان سے گذر نہ تھا، اور اس کی چھت اور دیواریں سیاہ رنگ سے رنگی ہوئی تھیں، کمرہ اندر سے بند تھا، کہ وفعتہ زور سے ایک تڑاقا ہوا، مسٹر موصوف کے استاد پروفیسر بون باہر تھے، وہ یہ آواز سن کر دوڑے کمرہ کے اندر انھوں نے جھانکا تو معلوم ہوا بجلی کی روشنی ہورہی ہے، ایک ہتھوڑا لے کر انہوں نے دروازہ توڑا اور اندر گئے تو دیکھا کہ مسٹر ہیورڈ خون میں شرابور پڑے ہوئے ہیں اور دیکھتے ہی دیکھتے ختم ہوگئے، پروفیسر بون کی رائے میں جس آلہ سے وہ تجربہ کررہے تھے، اتفاقاً پھٹ گیا اور اس کے اندر جو زہریلی گیس تھی، اس کے صدمہ سے ان کی گردن سخت مجروح ہوئی اور یہی باعث ہلاکت ہوا۔ (فروری ۱۹۲۱ء)

المنھج اللغوي في التفسير و تاريخه

The Holy Quran was revealed in Arabic Language, it is, therefore necessary to seek Arabic Diction to gain the direct guidance from it. The companions of Holy Prophetr, Tabeen, and the reverent Imams strictly rebuked those interpreters who interpret the Holy Quran without having command over Arabic Language. The verses of Quran that are clear in comprehension, explicit and easy, do require the source of interpretation as “Arabic Diction”. This method highlights the positive trends to Arabic Diction. But in the matter of ambiguity and resemblance in verses and deduction of Masael, this Diction will be given second priority. Mere Diction and Arabic Socio-Diction may not be titled as most authentic. Diction is not the ‘last word. ’ The very first priority will be given to the verses of Quran, Hadith e Nabvi and Quotations of Companions of Holy Prophetr. The companions themselves were the native Arabs but they used to do consult some Quranic terms with the Holy Prophetr. As time passed, some strayed sects and atheists ignored this positive trend (Tafseer-bil-Mathur), and accustomed a new trend of interpretation of Holy Quran i. E. Depending upon Arabic Diction only so that they may endorse their own thoughts. It was a negative source of interpreting the Holy Quran i. E. Only by Arabic Diction. The present article explores its historical perspectives after evaluating its negative trends. The Motazila sect got this trend nourished. The representing interpretations of Holy Quran of this trend have been analyzed in this article. At the end, Molana Ameen Ahsan Islahi’s approach to Diction and his Tafseer ‘Tadabbur e Quran’ has been evaluated.

Physiological and Molecular Characterization of Two Genetically Diverse Spring Wheat Triticum Aestivum L. Cultivars for Salt Tolerance

Hydroponic experiments were conducted to appraise variation in the salt tolerance potential of two wheat cultivars (salt tolerant, S-24 and moderately salt sensitive MH-97) at different growth stages. Salinity stress caused a marked reduction in plant biomass and grain yield of both wheat cultivars. However, cv. S-24 was superior to cv. MH-97 in maintaining higher plant biomass and grain yield under saline stress. Furthermore, salinity caused a significant variation in different physiological attributes measured at different growth stages. For example, salt stress caused a marked reduction in net photosynthetic and transpiration rate in both wheat cultivars but to a varying extent at different growth stages. Higher photosynthetic and transpiration rates were recorded at the boot stage than at other growth stages in both wheat cultivars. The response of other gas exchange attributes was also variable at different growth stages. Salt sensitive wheat cultivar MH-97 was more prone to salt-induced adverse effects on gas exchange attributes as compared to cv. S-24. Salt stress caused considerable reduction in different water relation attributes of wheat plants. A significant reduction in leaf water, osmotic and turgor potentials was recorded in both wheat cultivars at different growth stages. Maximal reduction in leaf water potential was recorded at the reproductive stage in both wheat cultivars. In contrast, maximal turgor potential was observed at the boot stage. Salt-induced adverse effects of salinity on different water relation attributes were more prominent in cv. MH-97 as compared to those in cv. S-24. The integrity of PS II was greatly perturbed in both wheat cultivars at different growth stages and this salt-induced damage to PS II was more in cv. MH-97. A significant alteration in different biochemical attributes was also observed in both wheat cultivars at different growth stages. For example, salt stress caused a substantial decrease in chlorophyll pigments, ascorbic acid, phenolics and tocopherols. In contrast, it increased the endogenous levels of ROS (H2O2), MDA, total soluble proteins, proline, glycine betaine and activities of enzymatic antioxidants (SOD, POD, CAT, APX). These biochemical attributes exhibited significant salt-induced variation at different growth stages in both wheat cultivars. For example, maximum accumulation of glycine betaine and proline was recorded at the early growth stages (vegetative and boot). However, cv. S-24 showed higher accumulation of these two organic osmolytes and this could be the reason for maintenance of higher turgor than that of cv. MH-97 under stress conditions. The activities of various enzymatic antioxidants increased markedly in both wheat cultivars, particularly at the vegetative stage. However, cv. S-24 exhibited consistent increase in the activities of various enzymatic antioxidants, whereas, this phenomena occurred erratically in cv. MH-97 at different growth stages. Salt stress significantly increased the endogenous levels of toxic ions (Na+and Cl-) and decreased essential cations (K+ and Ca2+) in both wheat cultivars at different growth stages. Furthermore, K+/Na+ and Ca2+/Na+ ratios decreased markedly due to salt stress in both wheat cultivars at different growth stages and this salt-induced reduction was more prominent in cv. MH-97. Moreover, higher K+/Na+ and Ca2+/Na+ ratios were recorded at early growth stages in both wheat cultivars. It can be inferred from the results that wheat plants are more prone to adverse effects of salinity stress at early growth stages than that at the reproductive stage.